7Y5P

Crystal structure of CmnC in complex with L-arginine and alpha-KG

Summary for 7Y5P

• Entry DOI: 10.2210/pdb7y5p/pdb
• Descriptor: CmnC, FE (III) ION, 2-OXOGLUTARIC ACID, ... (5 entities in total)
• Functional Keywords: hydroxylase, oxygenase, oxidoreductase
• Biological source: Saccharothrix mutabilis subsp. capreolus
• Total number of polymer chains: 2
• Total formula weight: 78698.31

Authors

Hsiao, Y.H.,Huang, S.J.,Lin, E.C.,Lee, Y.C.,Chang, C.Y. (deposition date: 2022-06-17, release date: 2023-07-05, Last modification date: 2023-11-29)

• Primary citation: Hsiao, Y.H.,Huang, S.J.,Lin, E.C.,Hsiao, P.Y.,Toh, S.I.,Chen, I.H.,Xu, Z.,Lin, Y.P.,Liu, H.J.,Chang, C.Y.; Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.; Front Chem, 10:1001311-1001311, 2022; PubMed: 36176888; DOI: 10.3389/fchem.2022.1001311

Experimental method

X-RAY DIFFRACTION (1.7 Å)