6K4P
| Crystal structure of xCas9 in complex with sgRNA and DNA (TGG PAM) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (28-MER), PHOSPHATE ION, ... | 著者 | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | 登録日 | 2019-05-25 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease. Plos Biol., 17, 2019
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2ZCF
| Mutational study on Alpha-Gln90 of Fe-type nitrile hydratase from Rhodococcus sp. N771 | 分子名称: | FE (III) ION, MAGNESIUM ION, Nitrile hydratase subunit alpha, ... | 著者 | Takarada, H, Kawano, Y, Hashimoto, K, Nakayama, H, Ueda, S, Yohda, M, Kamiya, N, Dohmae, N, Maeda, M, Odaka, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-11-08 | 公開日 | 2007-11-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Mutational study on alphaGln90 of Fe-type nitrile hydratase from Rhodococcus sp. N771 Biosci.Biotechnol.Biochem., 70, 2006
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5Z4U
| Crystal Structure of T2R-TTL complex with 7a3 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(4-ethoxyphenyl)-1-methyl-3-(3,4,5-trimethoxyphenyl)-1H-pyrazole, CALCIUM ION, ... | 著者 | Lai, Q, Wang, Y, Yang, J, Yao, Y. | 登録日 | 2018-01-14 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | Crystal Structure of T2R-TTL complex with 7a3 To Be Published
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6K4U
| Crystal structure of xCas9 in complex with sgRNA and DNA (TGA PAM) | 分子名称: | CRISPR-associated endonuclease Cas9, non-target DNA, sgRNA, ... | 著者 | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | 登録日 | 2019-05-27 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease. Plos Biol., 17, 2019
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6K4S
| Crystal structure of xCas9 in complex with sgRNA and DNA (TGC PAM) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, non-targeted DNA, sgRNA, ... | 著者 | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | 登録日 | 2019-05-26 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease. Plos Biol., 17, 2019
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5H01
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6K4Q
| Crystal structure of xCas9 in complex with sgRNA and DNA (CGG PAM) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (28-MER), DNA (5'-D(*AP*AP*AP*CP*GP*GP*TP*AP*TP*TP*G)-3'), ... | 著者 | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | 登録日 | 2019-05-26 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease. Plos Biol., 17, 2019
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5GQ9
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7CJB
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6K57
| Crystal structure of dCas9 in complex with sgRNA and DNA (CGA PAM) | 分子名称: | CRISPR-associated endonuclease Cas9, non-target DNA, sgRNA, ... | 著者 | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | 登録日 | 2019-05-28 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease. Plos Biol., 17, 2019
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3A2E
| Crystal structure of ginkbilobin-2, the novel antifungal protein from Ginkgo biloba seeds | 分子名称: | Ginkbilobin-2 | 著者 | Miyakawa, T, Miyazono, K, Sawano, Y, Hatano, K, Tanokura, M. | 登録日 | 2009-05-13 | 公開日 | 2009-06-02 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Crystal structure of ginkbilobin-2 with homology to the extracellular domain of plant cysteine-rich receptor-like kinases Proteins, 77, 2009
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2KLJ
| Solution Structure of gammaD-Crystallin with RDC and SAXS | 分子名称: | Gamma-crystallin D | 著者 | Wang, J, Zuo, X, Yu, P, Byeon, I, Jung, J, Gronenborn, A.M, Wang, Y. | 登録日 | 2009-07-06 | 公開日 | 2009-10-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR, SOLUTION SCATTERING | 主引用文献 | Determination of multicomponent protein structures in solution using global orientation and shape restraints. J.Am.Chem.Soc., 131, 2009
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6IFY
| Type III-A Csm complex, Cryo-EM structure of Csm-CTR1 | 分子名称: | CTR1, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-21 | 公開日 | 2018-12-12 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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6IFL
| Cryo-EM structure of type III-A Csm-NTR complex | 分子名称: | NTR, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-20 | 公開日 | 2018-12-12 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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5XWY
| Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex | 分子名称: | A type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, Cas13a, RNA (59-MER) | 著者 | Zhang, X, Wang, Y, Ma, J, Liu, L, Li, X, Li, Z, You, L, Wang, J, Wang, M. | 登録日 | 2017-06-30 | 公開日 | 2017-09-13 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a. Cell, 170, 2017
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8FXT
| Escherichia coli periplasmic Glucose-Binding Protein glucose complex: Acrylodan conjugate attached at W183C | 分子名称: | 1-[6-(dimethylamino)naphthalen-2-yl]propan-1-one, CALCIUM ION, D-galactose/methyl-galactoside binding periplasmic protein MglB, ... | 著者 | Allert, M.J, Kumar, S, Wang, Y, Beese, L.S, Hellinga, H.W. | 登録日 | 2023-01-25 | 公開日 | 2023-08-30 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching. Commun Chem, 6, 2023
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5YEL
| Crystal structure of CTCF ZFs6-11-gb7CSE | 分子名称: | DNA (26-MER), Transcriptional repressor CTCF, ZINC ION | 著者 | Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. | 登録日 | 2017-09-18 | 公開日 | 2017-11-29 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
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5YEH
| Crystal structure of CTCF ZFs4-8-eCBS | 分子名称: | DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*CP*CP*GP*CP*TP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*AP*GP*CP*GP*GP*AP*AP*AP*CP*CP*G)-3'), Transcriptional repressor CTCF, ... | 著者 | Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. | 登録日 | 2017-09-17 | 公開日 | 2017-11-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.328 Å) | 主引用文献 | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
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5YEF
| Crystal structure of CTCF ZFs2-8-Hs5-1aE | 分子名称: | DNA (27-MER), Transcriptional repressor CTCF, ZINC ION | 著者 | Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. | 登録日 | 2017-09-17 | 公開日 | 2017-11-29 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.807 Å) | 主引用文献 | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
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8FDU
| Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi (local refined on AAA3-AAA5 and LIS1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, Platelet-activating factor acetylhydrolase IB subunit beta,Platelet-activating factor acetylhydrolase IB subunit beta,human LIS1 protein with a SNAP tag | 著者 | Ton, W, Wang, Y, Chai, P. | 登録日 | 2022-12-04 | 公開日 | 2023-06-21 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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5Z10
| Structure of the mechanosensitive Piezo1 channel | 分子名称: | Piezo-type mechanosensitive ion channel component 1 | 著者 | Zhao, Q, Zhou, H, Chi, S, Wang, Y, Wang, J, Geng, J, Wu, K, Liu, W, Zhang, T, Dong, M.-Q, Wang, J, Li, X, Xiao, B. | 登録日 | 2017-12-22 | 公開日 | 2018-01-31 | 最終更新日 | 2020-01-29 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Structure and mechanogating mechanism of the Piezo1 channel. Nature, 554, 2018
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6IFZ
| Type III-A Csm complex, Cryo-EM structure of Csm-CTR2-ssDNA complex | 分子名称: | CTR2, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-21 | 公開日 | 2018-12-12 | 最終更新日 | 2019-01-23 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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6IFN
| Crystal structure of Type III-A CRISPR Csm complex | 分子名称: | MANGANESE (II) ION, RNA (32-MER), Type III-A CRISPR-associated RAMP protein Csm3, ... | 著者 | You, L, Wang, J, Wang, Y. | 登録日 | 2018-09-20 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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8FCY
| Engineered human dynein motor domain in microtubule-bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase | 著者 | Ton, W, Wang, Y, Chai, P. | 登録日 | 2022-12-01 | 公開日 | 2023-06-21 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FDT
| Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ... | 著者 | Ton, W, Wang, Y, Chai, P. | 登録日 | 2022-12-04 | 公開日 | 2023-06-21 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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