7FH8
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![BU of 7fh8 by Molmil](/molmil-images/mine/7fh8) | Friedel-Crafts alkylation enzyme CylK mutant H391A | 分子名称: | 2-[(5S,10S)-11-[3,5-bis(oxidanyl)phenyl]-10-methyl-undecan-5-yl]-5-[(2S,7R)-7-fluoranyl-2-methyl-undecyl]benzene-1,3-diol, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wang, H.Q, Wei, Z, Xiang, Z. | 登録日 | 2021-07-29 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Structural Basis for the Friedel-Crafts Alkylation in Cylindrocyclophane Biosynthesis ACS Catal., 12, 2022
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7FH6
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![BU of 7fh6 by Molmil](/molmil-images/mine/7fh6) | Friedel-Crafts alkylation enzyme CylK | 分子名称: | CALCIUM ION, CHLORIDE ION, CylK, ... | 著者 | Liu, L, Wang, H.Q, Xiang, Z. | 登録日 | 2021-07-29 | 公開日 | 2022-02-16 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural Basis for the Friedel-Crafts Alkylation in Cylindrocyclophane Biosynthesis ACS Catal., 12, 2022
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7QUO
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6JHO
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![BU of 6jho by Molmil](/molmil-images/mine/6jho) | The complex crystal structure of Cagbeta with CagZ revealed a novel regulatory mechanism for T4SS coupling ATPase in Helicobacter pylori | 分子名称: | Cag pathogenicity island protein (Cag5), Cag pathogenicity island protein (Cag6) | 著者 | Wu, X, Zhao, Y, Sun, L, Ye, X, Jiang, M, Wang, Q, Wang, Q, Wu, Y. | 登録日 | 2019-02-18 | 公開日 | 2020-02-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The complex crystal structure of Cagbeta with CagZ revealed a novel regulatory mechanism in VirD4 coupling ATPase To Be Published
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7BHD
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![BU of 7bhd by Molmil](/molmil-images/mine/7bhd) | FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group | 分子名称: | NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ... | 著者 | Bridot, C, Bouckaert, J, Krammer, E.-M. | 登録日 | 2021-01-11 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors. J.Biol.Chem., 299, 2023
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5ZE3
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6K7O
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![BU of 6k7o by Molmil](/molmil-images/mine/6k7o) | Complex structure of LILRB4 and h128-3 antibody | 分子名称: | Leukocyte immunoglobulin-like receptor subfamily B member 4, h128-3 Fab heavy chain, h128-3 Fab light chain | 著者 | Song, H, Chai, Y, Xu, X, Gao, F.G. | 登録日 | 2019-06-08 | 公開日 | 2019-07-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.004 Å) | 主引用文献 | Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development. Cancer Immunol Res, 7, 2019
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4AV4
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![BU of 4av4 by Molmil](/molmil-images/mine/4av4) | FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl pyridine | 分子名称: | 3-(pyridin-3-yl)prop-2-yn-1-yl alpha-D-mannopyranoside, FIMH | 著者 | Bouckaert, J, Touaibia, M, Roos, G, Shiao, T.C, Wang, Q, Papadopoulos, A, Roy, R. | 登録日 | 2012-05-23 | 公開日 | 2012-06-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh. Biochemistry, 51, 2012
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4ATT
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![BU of 4att by Molmil](/molmil-images/mine/4att) | FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl para methoxy phenyl | 分子名称: | 3-(4-methoxyphenyl)prop-2-yn-1-yl alpha-D-mannopyranoside, FIMH | 著者 | Bouckaert, J, Touaibia, M, Roos, G, Shiao, T.C, Wang, Q, Papadopoulos, A, Roy, R. | 登録日 | 2012-05-09 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.251 Å) | 主引用文献 | Validation of Reactivity Descriptors to Assess the Aromatic Stacking within the Tyrosine Gate of Fimh. Acs Med.Chem.Lett., 4, 2013
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4AUJ
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![BU of 4auj by Molmil](/molmil-images/mine/4auj) | FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to para hydroxypropargyl phenyl | 分子名称: | 4-(3-hydroxyprop-1-yn-1-yl)phenyl alpha-D-mannopyranoside, FIMH | 著者 | Bouckaert, J, Touaibia, M, Roos, G, Shiao, T.C, Wang, Q, Papadopoulos, A, Roy, R. | 登録日 | 2012-05-17 | 公開日 | 2013-05-29 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.527 Å) | 主引用文献 | Validation of Reactivity Descriptors to Assess the Aromatic Stacking within the Tyrosine Gate of Fimh. Acs Med.Chem.Lett., 4, 2013
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8Z9A
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![BU of 8z9a by Molmil](/molmil-images/mine/8z9a) | Cryo-EM structure of the insect olfactory receptor OR5-Orco heterocomplex from Acyrthosiphon pisum bound with geranyl acetate | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Odorant receptor, ApisOR5, ... | 著者 | Wang, Y.D, Qiu, L, Guan, Z.Y, Wang, Q, Wang, G.R, Yin, P. | 登録日 | 2024-04-23 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for odorant recognition of the insect odorant receptor OR-Orco heterocomplex. Science, 384, 2024
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8Z9Z
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![BU of 8z9z by Molmil](/molmil-images/mine/8z9z) | Cryo-EM structure of the insect olfactory receptor OR5-Orco heterocomplex from Acyrthosiphon pisum | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Odorant receptor, ApisOR5, ... | 著者 | Wang, Y.D, Qiu, L, Guan, Z.Y, Wang, Q, Wang, G.R, Yin, P. | 登録日 | 2024-04-24 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis for odorant recognition of the insect odorant receptor OR-Orco heterocomplex. Science, 384, 2024
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8HLF
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![BU of 8hlf by Molmil](/molmil-images/mine/8hlf) | Crystal structure of DddK-DMSOP complex | 分子名称: | 3-[dimethyl(oxidanyl)-$l^{4}-sulfanyl]propanoic acid, MANGANESE (II) ION, Novel protein with potential Cupin domain | 著者 | Peng, M, Li, C.Y, Zhang, Y.Z. | 登録日 | 2022-11-30 | 公開日 | 2023-10-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | DMSOP-cleaving enzymes are diverse and widely distributed in marine microorganisms. Nat Microbiol, 8, 2023
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8HLE
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![BU of 8hle by Molmil](/molmil-images/mine/8hle) | Structure of DddY-DMSOP complex | 分子名称: | 3-[dimethyl(oxidanyl)-$l^{4}-sulfanyl]propanoic acid, DMSP lyase DddY, ZINC ION | 著者 | Peng, M, Li, C.Y, Zhang, Y.Z. | 登録日 | 2022-11-30 | 公開日 | 2023-10-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | DMSOP-cleaving enzymes are diverse and widely distributed in marine microorganisms. Nat Microbiol, 8, 2023
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5Z9O
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8XZD
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7D5I
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![BU of 7d5i by Molmil](/molmil-images/mine/7d5i) | Structure of Mycobacterium smegmatis bd complex in the apo-form. | 分子名称: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome D ubiquinol oxidase subunit 1, HEME B/C, ... | 著者 | Wang, W, Gong, H, Gao, Y, Zhou, X, Rao, Z. | 登録日 | 2020-09-26 | 公開日 | 2021-06-23 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels. Nat Commun, 12, 2021
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8WKU
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![BU of 8wku by Molmil](/molmil-images/mine/8wku) | Complex structure of MjHKU4r-CoV-1 spike RBD bound to human CD26 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4 soluble form, MjHKU4r-CoV-1 spike RBD, ... | 著者 | Zhao, Z.N, Chai, Y, Gao, F. | 登録日 | 2023-09-28 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Molecular basis for receptor recognition and broad host tropism for merbecovirus MjHKU4r-CoV-1. Embo Rep., 25, 2024
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8XYZ
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![BU of 8xyz by Molmil](/molmil-images/mine/8xyz) | The structure of fox ACE2 and PT RBD complex | 分子名称: | Angiotensin-converting enzyme, Signal peptide, Spike protein S1, ... | 著者 | sun, J.Q. | 登録日 | 2024-01-20 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | The binding and structural basis of fox ACE2 to RBDs from different sarbecoviruses. Virol Sin, 2024
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8HDK
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![BU of 8hdk by Molmil](/molmil-images/mine/8hdk) | Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine and glutamate (minor class in symmetry) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S. | 登録日 | 2022-11-04 | 公開日 | 2023-03-29 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30, 2023
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7E1V
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![BU of 7e1v by Molmil](/molmil-images/mine/7e1v) | Cryo-EM structure of apo hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, CARDIOLIPIN, ... | 著者 | Zhou, S, Wang, W, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2021-02-03 | 公開日 | 2021-10-13 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates. Elife, 10, 2021
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7E1X
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![BU of 7e1x by Molmil](/molmil-images/mine/7e1x) | Cryo-EM structure of hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in presence of TB47 | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, 5-methoxy-2-methyl-~{N}-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]pyrazolo[1,5-a]pyridine-3-carboxamide, ... | 著者 | Zhou, S, Wang, W, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2021-02-03 | 公開日 | 2021-10-27 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates. Elife, 10, 2021
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7E1W
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![BU of 7e1w by Molmil](/molmil-images/mine/7e1w) | Cryo-EM structure of hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in the presence of Q203 | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, 6-chloranyl-2-ethyl-N-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide, ... | 著者 | Zhou, S, Wang, W, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2021-02-03 | 公開日 | 2021-10-27 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates. Elife, 10, 2021
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8IFF
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![BU of 8iff by Molmil](/molmil-images/mine/8iff) | Cryo-EM structure of Arabidopsis phytochrome A. | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A | 著者 | Ma, L, Zhou, C, Wang, J, Guan, Z, Yin, P. | 登録日 | 2023-02-17 | 公開日 | 2023-08-02 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Plant phytochrome A in the Pr state assembles as an asymmetric dimer. Cell Res., 33, 2023
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7ELM
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![BU of 7elm by Molmil](/molmil-images/mine/7elm) | Structure of Csy-AcrIF24 | 分子名称: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | 著者 | Zhang, L, Feng, Y. | 登録日 | 2021-04-12 | 公開日 | 2022-04-20 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
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