4AV4

FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl pyridine

Summary for 4AV4

• Entry DOI: 10.2210/pdb4av4/pdb
• Related: 4ATT 4AUJ 4AUU 4AUY 4AV0 4AV5
• Descriptor: FIMH, 3-(pyridin-3-yl)prop-2-yn-1-yl alpha-D-mannopyranoside (3 entities in total)
• Functional Keywords: cell adhesion, fimbriae, variable immunoglobulin fold, urinary tract infection
• Biological source: ESCHERICHIA COLI
• Total number of polymer chains: 1
• Total formula weight: 17211.13

Authors

Bouckaert, J.,Touaibia, M.,Roos, G.,Shiao, T.C.,Wang, Q.,Papadopoulos, A.,Roy, R. (deposition date: 2012-05-23, release date: 2012-06-27, Last modification date: 2023-12-20)

• Primary citation: Wellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J.; The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh.; Biochemistry, 51:4790-, 2012; PubMed: 22657089; DOI: 10.1021/BI300251R

Experimental method

X-RAY DIFFRACTION (1.9 Å)