4AV5

Structure of a triclinic crystal of the FimH lectin domain in complex with a propynyl biphenyl alpha-D-mannoside, at 1.4 A resolution

Summary for 4AV5

Entry DOI	10.2210/pdb4av5/pdb
Related	4ATT 4AUJ 4AUU 4AUY 4AV0 4AV4 4AVH 4AVI 4AVJ 4AVK
Descriptor	FIMH, (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-[3-(4-phenylphenyl)prop-2-ynoxy]oxane-3,4,5-triol, SULFATE ION, ... (4 entities in total)
Functional Keywords	cell adhesion, bacterial adhesin type 1 fimbriae, urinary tract infection, variable immunoglobulin fold
Biological source	ESCHERICHIA COLI
Total number of polymer chains	4
Total formula weight	69437.09
Authors	Wellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J. (deposition date: 2012-05-23, release date: 2012-06-27, Last modification date: 2023-12-20)
Primary citation	Wellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J. The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh. Biochemistry, 51:4790-, 2012 Cited by PubMed: 22657089 DOI: 10.1021/BI300251R PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation