4AV5
Structure of a triclinic crystal of the FimH lectin domain in complex with a propynyl biphenyl alpha-D-mannoside, at 1.4 A resolution
Summary for 4AV5
Entry DOI | 10.2210/pdb4av5/pdb |
Related | 4ATT 4AUJ 4AUU 4AUY 4AV0 4AV4 4AVH 4AVI 4AVJ 4AVK |
Descriptor | FIMH, (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-[3-(4-phenylphenyl)prop-2-ynoxy]oxane-3,4,5-triol, SULFATE ION, ... (4 entities in total) |
Functional Keywords | cell adhesion, bacterial adhesin type 1 fimbriae, urinary tract infection, variable immunoglobulin fold |
Biological source | ESCHERICHIA COLI |
Total number of polymer chains | 4 |
Total formula weight | 69437.09 |
Authors | Wellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J. (deposition date: 2012-05-23, release date: 2012-06-27, Last modification date: 2023-12-20) |
Primary citation | Wellens, A.,Lahmann, M.,Touaibia, M.,Vaucher, J.,Oscarson, S.,Roy, R.,Remaut, H.,Bouckaert, J. The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh. Biochemistry, 51:4790-, 2012 Cited by PubMed: 22657089DOI: 10.1021/BI300251R PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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