7VXE
 
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7VXC
 | | SARS-CoV-2 Kappa variant spike protein in C3 state | | 分子名称: | Angiotensin-converting enzyme 2, Spike glycoprotein | | 著者 | Xu, C, Cong, Y. | | 登録日 | 2021-11-12 | | 公開日 | 2021-12-22 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Conformational dynamics of the Beta and Kappa SARS-CoV-2 spike proteins and their complexes with ACE2 receptor revealed by cryo-EM.
Nat Commun, 12, 2021
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7VXI
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7VXK
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7VXB
 | | SARS-CoV-2 Kappa variant spike protein in C2b state | | 分子名称: | Angiotensin-converting enzyme 2, Spike glycoprotein | | 著者 | Xu, C, Cong, Y. | | 登録日 | 2021-11-12 | | 公開日 | 2021-12-22 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Conformational dynamics of the Beta and Kappa SARS-CoV-2 spike proteins and their complexes with ACE2 receptor revealed by cryo-EM.
Nat Commun, 12, 2021
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7VXM
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8WCE
 | | Cryo-EM structure of a protein-RNA complex | | 分子名称: | MAGNESIUM ION, RNA (31-MER), RNA (66-MER), ... | | 著者 | Li, Z. | | 登録日 | 2023-09-11 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Molecular mechanism for target RNA recognition and cleavage of Cas13h.
Nucleic Acids Res., 52, 2024
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7WEV
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8X3R
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8XFD
 | | Crystal structure of pyruvate kinase tetramer in complex with allosteric activator, Mitapivat (MTPV, AG-348) | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, Isoform L-type of Pyruvate kinase PKLR, MAGNESIUM ION, ... | | 著者 | Sun, R, Achour, A. | | 登録日 | 2023-12-13 | | 公開日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High Resolution Crystal Structure of the Pyruvate Kinase Tetramer in Complex with the Allosteric Activator Mitapivat/AG-348
Crystals, 2024
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8X3S
 | | Crystal structure of human WDR5 in complex with PTEN | | 分子名称: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, WD repeat-containing protein 5 | | 著者 | Liu, Y, Huang, X, Shang, X. | | 登録日 | 2023-11-14 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | The NTE domain of PTEN alpha / beta promotes cancer progression by interacting with WDR5 via its SSSRRSS motif.
Cell Death Dis, 15, 2024
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8Y6U
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8WD8
 | | Cryo-EM structure of TtdAgo-guide DNA-target DNA complex | | 分子名称: | Argonaute family protein, Guide DNA, MAGNESIUM ION, ... | | 著者 | Zhuang, L. | | 登録日 | 2023-09-14 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular mechanism for target recognition, dimerization, and activation of Pyrococcus furiosus Argonaute.
Mol.Cell, 84, 2024
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8HAF
 | | PTHrP-PTH1R-Gs complex | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhao, L, Xu, H.E, Yuan, Q. | | 登録日 | 2022-10-26 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1.
Acta Pharmacol.Sin., 44, 2023
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8HA0
 | | Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1 | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhao, L, Xu, H.E, Yuan, Q. | | 登録日 | 2022-10-26 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | | 主引用文献 | Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1.
Acta Pharmacol.Sin., 44, 2023
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8HAO
 | | Human parathyroid hormone receptor-1 dimer | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha, ... | | 著者 | Zhao, L, Xu, H.E, Yuan, Q. | | 登録日 | 2022-10-26 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | | 主引用文献 | Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1.
Acta Pharmacol.Sin., 44, 2023
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8H4U
 | | Cryo-EM structure of a riboendonuclease | | 分子名称: | CRISPR-associated endonuclease Cas9 | | 著者 | Li, Z, Wang, F. | | 登録日 | 2022-10-11 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural Basis for the Ribonuclease Activity of a Thermostable CRISPR-Cas13a from Thermoclostridium caenicola.
J.Mol.Biol., 435, 2023
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8H41
 | | Crystal structure of a decarboxylase from Trichosporon moniliiforme in complex with o-nitrophenol | | 分子名称: | MAGNESIUM ION, O-NITROPHENOL, Salicylate decarboxylase | | 著者 | Gao, J, Zhao, Y.P, Li, Q, Liu, W.D, Sheng, X. | | 登録日 | 2022-10-09 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | A Combined Computational-Experimental Study on the Substrate Binding and Reaction Mechanism of Salicylic Acid Decarboxylase
Catalysts, 12, 2022
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8I6K
 | | Structure of hMNDA HIN with dsDNA | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ... | | 著者 | Li, Y.L, Jin, T.C. | | 登録日 | 2023-01-28 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural mechanism of dsDNA recognition by the hMNDA HIN domain: New insights into the DNA-binding model of a PYHIN protein.
Int.J.Biol.Macromol., 245, 2023
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8IUO
 | | respiratory syncytial virus nucleocapsid-like assembly | | 分子名称: | Nucleoprotein, RNA (35-MER) | | 著者 | Wang, Y, Luo, Y, Ling, X, Luo, B, Jia, G, Dong, H, Su, Z. | | 登録日 | 2023-03-24 | | 公開日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Cryo-EM structure of the nucleocapsid-like assembly of respiratory syncytial virus.
Signal Transduct Target Ther, 8, 2023
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7YG7
 | | Structure of the Spring Viraemia of Carp Virus ribonucleoprotein Complex | | 分子名称: | Nucleoprotein, RNA (99-mer) | | 著者 | Liu, B, Wang, Z.X, Yang, T, Yu, D.Q, Ouyang, Q. | | 登録日 | 2022-07-11 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure of the Spring Viraemia of Carp Virus Ribonucleoprotein Complex Reveals Its Assembly Mechanism and Application in Antiviral Drug Screening.
J.Virol., 97, 2023
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7EN0
 | | Structure and Activity of SLAC1 Channels for Stomatal Signaling in Leaves | | 分子名称: | DIUNDECYL PHOSPHATIDYL CHOLINE, SLow Anion Channel 1, SPHINGOSINE | | 著者 | Deng, Y, Kashtoh, H, Wang, Q, Zhen, G, Li, Q, Tang, L, Gao, H, Zhang, C, Qin, L, Su, M, Li, F, Huang, X, Wang, Y, Xie, Q, Clarke, O.B, Hendrickson, W.A, Chen, Y. | | 登録日 | 2021-04-15 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structure and activity of SLAC1 channels for stomatal signaling in leaves.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7VUZ
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12, state2 | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Li, Y, Yang, F. | | 登録日 | 2021-11-04 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
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7VV4
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7VDM
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