8HAF

PTHrP-PTH1R-Gs complex

Summary for 8HAF

• Entry DOI: 10.2210/pdb8haf/pdb
• EMDB information: 34585 34587 34598
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
• Functional Keywords: pth1r, gpcr, lipid binding protein-hormone-immune system complex, lipid binding protein/hormone/immune system
• Biological source: Bos taurus (cattle); More
• Total number of polymer chains: 6
• Total formula weight: 172705.61

Authors

Zhao, L.,Xu, H.E.,Yuan, Q. (deposition date: 2022-10-26, release date: 2022-12-21, Last modification date: 2023-05-31)

• Primary citation: Zhao, L.H.,Yuan, Q.N.,Dai, A.T.,He, X.H.,Chen, C.W.,Zhang, C.,Xu, Y.W.,Zhou, Y.,Wang, M.W.,Yang, D.H.,Xu, H.E.; Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1.; Acta Pharmacol.Sin., 44:1227-1237, 2023; PubMed: 36482086; DOI: 10.1038/s41401-022-01032-z

Experimental method

ELECTRON MICROSCOPY (3.25 Å)