1YLP
 
 | | Atomic resolution structure of CTX-M-27 beta-lactamase | | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-27 | | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability.
J.Mol.Biol., 348, 2005
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3BUA
 | | Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex | | 分子名称: | DNA cross-link repair 1B protein, Telomeric repeat-binding factor 2 | | 著者 | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | | 登録日 | 2008-01-02 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
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1YMS
 | | X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with nafcinin-like boronic acid inhibitor | | 分子名称: | [(2-ETHOXY-1-NAPHTHOYL)AMINO]METHYLBORONIC ACID, beta-lactamase CTX-M-9 | | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-21 | | 公開日 | 2005-04-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases.
J.Am.Chem.Soc., 127, 2005
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1YLZ
 | | X-ray crystallographic structure of CTX-M-14 beta-lactamase complexed with ceftazidime-like boronic acid | | 分子名称: | BETA-LACTAMASE CTX-M-14, PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE | | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases.
J.Am.Chem.Soc., 127, 2005
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1YMX
 | | X-ray crystallographic structure of CTX-M-9 beta-lactamase covalently linked to cefoxitin | | 分子名称: | (2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, beta-lactamase CTX-M-9 | | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-21 | | 公開日 | 2005-04-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases.
J.Am.Chem.Soc., 127, 2005
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3BU8
 | | Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex | | 分子名称: | TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2 | | 著者 | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | | 登録日 | 2008-01-02 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
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3BQO
 | | Crystal Structure of TRF1 TRFH domain and TIN2 peptide complex | | 分子名称: | TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 1 | | 著者 | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | | 登録日 | 2007-12-20 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
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4L3N
 | | Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | | 著者 | Chen, Y, Rajashankar, K.R, Yang, Y, Agnihothram, S.S, Liu, C, Lin, Y.-L, Baric, R.S, Li, F. | | 登録日 | 2013-06-06 | | 公開日 | 2013-07-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Crystal structure of the receptor-binding domain from newly emerged middle East respiratory syndrome coronavirus.
J.Virol., 87, 2013
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8OEU
 | | Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4) | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | | 登録日 | 2023-03-13 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structure of the transcribing RNA polymerase II-Elongin complex.
Nat.Struct.Mol.Biol., 30, 2023
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8OEW
 | | Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite structure, structure 2) | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | | 登録日 | 2023-03-13 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of the transcribing RNA polymerase II-Elongin complex.
Nat.Struct.Mol.Biol., 30, 2023
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8OF0
 | | Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | | 登録日 | 2023-03-13 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structure of the transcribing RNA polymerase II-Elongin complex.
Nat.Struct.Mol.Biol., 30, 2023
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8OEV
 | | Structure of the mammalian Pol II-SPT6-Elongin complex, lacking ELOA latch (composite structure, structure 3) | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | | 登録日 | 2023-03-13 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Structure of the transcribing RNA polymerase II-Elongin complex.
Nat.Struct.Mol.Biol., 30, 2023
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2D28
 | | Structure of the N-terminal domain of XpsE (crystal form P43212) | | 分子名称: | CACODYLATE ION, type II secretion ATPase XpsE | | 著者 | Chen, Y, Shiue, S.-J, Huang, C.-W, Chang, J.-L, Chien, Y.-L, Hu, N.-T, Chan, N.-L. | | 登録日 | 2005-09-03 | | 公開日 | 2005-09-20 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and Function of the XpsE N-Terminal Domain, an Essential Component of the Xanthomonas campestris Type II Secretion System
J.Biol.Chem., 280, 2005
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6AWJ
 | | Staphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Deoxy-MeO-N5Pan with pantothenate present in reaction | | 分子名称: | (2R)-2-hydroxy-N-{3-[(5-methoxypentyl)amino]-3-oxopropyl}-3,3-dimethylbutanamide, ADENOSINE-5'-DIPHOSPHATE, Type II pantothenate kinase | | 著者 | Chen, Y, Antoshchenko, T, Strauss, E, Barnard, L, Huang, Y.H. | | 登録日 | 2017-09-05 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase.
To Be Published
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6AWI
 | | Staphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Deoxy-N5Pan | | 分子名称: | (2R)-2-hydroxy-3,3-dimethyl-N-[3-oxo-3-(pentylamino)propyl]butanamide, ADENOSINE-5'-DIPHOSPHATE, Type II pantothenate kinase | | 著者 | Chen, Y, Antoshchenko, T, Strauss, E, Barnard, L, Huang, Y.H. | | 登録日 | 2017-09-05 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase.
To Be Published
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6AVP
 | | Staphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Phosphate-MeO-N5Pan | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-(5-methoxypentyl)-beta-alaninamide, ... | | 著者 | Chen, Y, Antoshchenko, T, Strauss, E, Barnard, L, Huang, Y.H. | | 登録日 | 2017-09-04 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase.
To Be Published
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6AWG
 | | Staphylococcus aureus Type II pantothenate kinase in complex with nucleotides and pantothenate analog Deoxy-N190Pan | | 分子名称: | (2R)-N-(3-{[(2H-1,3-benzodioxol-5-yl)methyl]amino}-3-oxopropyl)-2-hydroxy-3,3-dimethylbutanamide, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Chen, Y, Antoshchenko, T, Strauss, E, Barnard, L, Huang, Y.H. | | 登録日 | 2017-09-05 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase.
To Be Published
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2D27
 | | Structure of the N-terminal domain of XpsE (crystal form I4122) | | 分子名称: | type II secretion ATPase XpsE | | 著者 | Chen, Y, Shiue, S.-J, Huang, C.-W, Chang, J.-L, Chien, Y.-L, Hu, N.-T, Chan, N.-L. | | 登録日 | 2005-09-03 | | 公開日 | 2005-09-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure and Function of the XpsE N-Terminal Domain, an Essential Component of the Xanthomonas campestris Type II Secretion System
J.Biol.Chem., 280, 2005
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3FN3
 | | Dimeric Structure of PD-L1 | | 分子名称: | Programmed cell death 1 ligand 1 | | 著者 | Chen, Y, Gao, F, Liu, P, Chu, F, Qi, J, Gao, G.F. | | 登録日 | 2008-12-23 | | 公開日 | 2009-12-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A dimeric structure of PD-L1: functional units or evolutionary relics?
Protein Cell, 1, 2010
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6AWH
 | | Staphylococcus aureus Type II pantothenate kinase in complex with ATP and pantothenate analog Deoxy-MeO-N5Pan | | 分子名称: | (2R)-2-hydroxy-N-{3-[(5-methoxypentyl)amino]-3-oxopropyl}-3,3-dimethylbutanamide, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Chen, Y, Antoshchenko, T, Strauss, E, Barnard, L, Huang, Y.H. | | 登録日 | 2017-09-05 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase.
To Be Published
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2FEY
 | | The structure of stem loop IV of Tetrahymena telomerase RNA | | 分子名称: | stem-loop IV of Tetrahymena telomerase RNA | | 著者 | Chen, Y, Fender, J, Legassie, J.D, Jarstfer, M.B, Bryan, T.M, Varani, G. | | 登録日 | 2005-12-16 | | 公開日 | 2006-06-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of stem-loop IV of Tetrahymena telomerase RNA.
Embo J., 25, 2006
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2FFY
 | | AmpC beta-lactamase N289A mutant in complex with a boronic acid deacylation transition state analog compound SM3 | | 分子名称: | (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID, Beta-lactamase, PHOSPHATE ION, ... | | 著者 | Chen, Y, Minasov, G, Roth, T.A, Prati, F, Shoichet, B.K. | | 登録日 | 2005-12-20 | | 公開日 | 2006-03-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution
J.Am.Chem.Soc., 128, 2006
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4IK4
 | | High resolution structure of GCaMP3 at pH 5.0 | | 分子名称: | CALCIUM ION, RCaMP, Green fluorescent protein | | 著者 | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | | 登録日 | 2012-12-25 | | 公開日 | 2014-02-05 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
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4IK9
 | | High resolution structure of GCaMP3 dimer form 2 at pH 7.5 | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, RCaMP, ... | | 著者 | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | | 登録日 | 2012-12-25 | | 公開日 | 2014-01-29 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
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4IK8
 | | High resolution structure of GCaMP3 dimer form 1 at pH 7.5 | | 分子名称: | CALCIUM ION, RCaMP, Green fluorescent protein | | 著者 | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | | 登録日 | 2012-12-25 | | 公開日 | 2014-02-05 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
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