1YLZ
X-ray crystallographic structure of CTX-M-14 beta-lactamase complexed with ceftazidime-like boronic acid
Summary for 1YLZ
Entry DOI | 10.2210/pdb1ylz/pdb |
Related | 1YLJ |
Descriptor | BETA-LACTAMASE CTX-M-14, PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE, ... (4 entities in total) |
Functional Keywords | ctx-m, beta-lactamase, transition state, ceftazidime, boronic acid, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 56946.26 |
Authors | Chen, Y.,Shoichet, B.,Bonnet, R. (deposition date: 2005-01-19, release date: 2005-04-26, Last modification date: 2023-08-23) |
Primary citation | Chen, Y.,Shoichet, B.,Bonnet, R. Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127:5423-5434, 2005 Cited by PubMed: 15826180DOI: 10.1021/ja042850a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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