6AWG
Staphylococcus aureus Type II pantothenate kinase in complex with nucleotides and pantothenate analog Deoxy-N190Pan
Summary for 6AWG
Entry DOI | 10.2210/pdb6awg/pdb |
Descriptor | Type II pantothenate kinase, ADENOSINE-5'-TRIPHOSPHATE, (2R)-N-(3-{[(2H-1,3-benzodioxol-5-yl)methyl]amino}-3-oxopropyl)-2-hydroxy-3,3-dimethylbutanamide, ... (5 entities in total) |
Functional Keywords | staphylococcus aureus, sapank, adp, atp, pantothenate analog, transferase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 4 |
Total formula weight | 119205.38 |
Authors | Chen, Y.,Antoshchenko, T.,Strauss, E.,Barnard, L.,Huang, Y.H. (deposition date: 2017-09-05, release date: 2018-09-12, Last modification date: 2024-03-13) |
Primary citation | Chen, Y.,Antoshchenko, T.,Strauss, E.,Barnard, L.,Huang, Y.H. Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase. To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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