6XFN
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![BU of 6xfn by Molmil](/molmil-images/mine/6xfn) | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with UAW243 | 分子名称: | 3C-like proteinase, GLYCEROL, UAW243 | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | 登録日 | 2020-06-15 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L. Sci Adv, 6, 2020
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6XBI
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![BU of 6xbi by Molmil](/molmil-images/mine/6xbi) | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW248 | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | 登録日 | 2020-06-06 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L. Sci Adv, 6, 2020
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6XBH
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![BU of 6xbh by Molmil](/molmil-images/mine/6xbh) | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW247 | 分子名称: | 3C-like proteinase, GLYCEROL, SODIUM ION, ... | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | 登録日 | 2020-06-06 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L. Sci Adv, 6, 2020
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6XA4
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![BU of 6xa4 by Molmil](/molmil-images/mine/6xa4) | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with UAW241 | 分子名称: | 3C-like proteinase, GLYCEROL, inhibitor UAW241 | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | 登録日 | 2020-06-03 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L. Sci Adv, 6, 2020
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6T36
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![BU of 6t36 by Molmil](/molmil-images/mine/6t36) | Crystal structure of the PTPN3 PDZ domain bound to the HBV core protein C-terminal peptide | 分子名称: | BROMIDE ION, Capsid protein, Tyrosine-protein phosphatase non-receptor type 3 | 著者 | Genera, M, Mechaly, A, Haouz, A, Caillet-Saguy, C. | 登録日 | 2019-10-10 | 公開日 | 2021-01-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein. Sci Rep, 11, 2021
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6XBG
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![BU of 6xbg by Molmil](/molmil-images/mine/6xbg) | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW246 | 分子名称: | 3C-like proteinase, GLYCEROL, SODIUM ION, ... | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | 登録日 | 2020-06-05 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L. Sci Adv, 6, 2020
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6RJD
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![BU of 6rjd by Molmil](/molmil-images/mine/6rjd) | Cryo-EM structure of St1Cas9-sgRNA-tDNA59-ntPAM complex. | 分子名称: | Streptococcus Thermophilus 1 Cas9, ntPAM, sgRNA (78-MER), ... | 著者 | Goulet, A, Chaves-Sanjuan, A, Cambillau, C. | 登録日 | 2019-04-26 | 公開日 | 2019-10-02 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6. Mol.Cell, 76, 2019
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6RJ9
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![BU of 6rj9 by Molmil](/molmil-images/mine/6rj9) | Cryo-EM structure of St1Cas9-sgRNA-tDNA20-AcrIIA6 monomeric assembly. | 分子名称: | AcrIIA6, CRISPR-associated endonuclease Cas9 1, sgRNA, ... | 著者 | Goulet, A, Chaves-Sanjuan, A, Cambillau, C. | 登録日 | 2019-04-26 | 公開日 | 2019-10-02 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6. Mol.Cell, 76, 2019
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6RJG
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![BU of 6rjg by Molmil](/molmil-images/mine/6rjg) | Cryo-EM structure of St1Cas9-sgRNA-AcrIIA6-tDNA59-ntPAM complex. | 分子名称: | AcrIIA6, Cas 9, ntPAM, ... | 著者 | Goulet, A, Chaves-Sanjuan, A, Cambillau, C. | 登録日 | 2019-04-26 | 公開日 | 2019-10-02 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6. Mol.Cell, 76, 2019
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6RJA
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![BU of 6rja by Molmil](/molmil-images/mine/6rja) | Cryo-EM structure of St1Cas9-sgRNA-tDNA20-AcrIIA6 dimeric assembly. | 分子名称: | AcrIIA6, CRISPR-associated endonuclease Cas9 1, RNA (78-MER), ... | 著者 | Goulet, A, Cambillau, C, Chaves-Sanjuan, A. | 登録日 | 2019-04-26 | 公開日 | 2019-10-02 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6. Mol.Cell, 76, 2019
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7Q5I
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![BU of 7q5i by Molmil](/molmil-images/mine/7q5i) | A glucose-based molecular rotor probes the catalytic site of glycogen phosphorylase. | 分子名称: | 2-cyano-3-[4-(dimethylamino)phenyl]-~{N}-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]propanamide, BETA-MERCAPTOETHANOL, CARBONATE ION, ... | 著者 | Neofytos, D.D, Chrysina, E.D. | 登録日 | 2021-11-03 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A glucose-based molecular rotor inhibitor of glycogen phosphorylase as a probe of cellular enzymatic function. Org.Biomol.Chem., 20, 2022
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8BUX
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![BU of 8bux by Molmil](/molmil-images/mine/8bux) | Rab-binding domain of human MiniBAR | 分子名称: | 1,2-ETHANEDIOL, Granule associated Rac and RHOG effector protein 1, MAGNESIUM ION, ... | 著者 | Pylypenko, O, Hammich, H, Houdusse, A. | 登録日 | 2022-12-01 | 公開日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | MiniBAR/KIAA0355 is a dual Rac and Rab effector that controls actin contractility
and trafficking for successful ciliogenesis To Be Published
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8BUY
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![BU of 8buy by Molmil](/molmil-images/mine/8buy) | Rac-binding domain of human MiniBAR | 分子名称: | 1,2-ETHANEDIOL, Granule associated Rac and RHOG effector protein 1, SULFATE ION | 著者 | Pylypenko, O, Hammich, H, Houdusse, A. | 登録日 | 2022-12-01 | 公開日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | MiniBAR/KIAA0355 is a dual Rac and Rab effector that controls actin contractility
and trafficking for successful ciliogenesis To Be Published
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6US8
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![BU of 6us8 by Molmil](/molmil-images/mine/6us8) | |
6US9
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![BU of 6us9 by Molmil](/molmil-images/mine/6us9) | |
6VLW
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![BU of 6vlw by Molmil](/molmil-images/mine/6vlw) | |
8IG0
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![BU of 8ig0 by Molmil](/molmil-images/mine/8ig0) | Crystal structure of menin in complex with DS-1594b | 分子名称: | (1R,2S,4R)-4-[[4-(5,6-dimethoxypyridazin-3-yl)phenyl]methylamino]-2-[methyl-[6-[2,2,2-tris(fluoranyl)ethyl]thieno[2,3-d]pyrimidin-4-yl]amino]cyclopentan-1-ol, DIMETHYL SULFOXIDE, Menin, ... | 著者 | Suzuki, M, Yoneyama, T, Imai, E. | 登録日 | 2023-02-20 | 公開日 | 2023-03-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1. Cancer Cell Int, 23, 2023
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5XOD
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![BU of 5xod by Molmil](/molmil-images/mine/5xod) | Crystal structure of human Smad2-Ski complex | 分子名称: | Mothers against decapentaplegic homolog 2, Ski oncogene | 著者 | Miyazono, K, Moriwaki, S, Ito, T, Tanokura, M. | 登録日 | 2017-05-27 | 公開日 | 2018-03-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | 主引用文献 | Hydrophobic patches on SMAD2 and SMAD3 determine selective binding to cofactors Sci Signal, 11, 2018
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5XOC
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![BU of 5xoc by Molmil](/molmil-images/mine/5xoc) | |
4K71
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![BU of 4k71 by Molmil](/molmil-images/mine/4k71) | Crystal structure of a high affinity Human Serum Albumin variant bound to the Neonatal Fc Receptor | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, SULFATE ION, ... | 著者 | Schmidt, M.M, Townson, S.A, Andreucci, A, Dombrowski, C, Erbe, D.V, King, B, Kovalchin, J.T, Masci, A, Murillo, A, Schirmer, E.B, Furfine, E.S, Barnes, T.M. | 登録日 | 2013-04-16 | 公開日 | 2013-10-23 | 最終更新日 | 2014-02-05 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface. Structure, 21, 2013
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5IHL
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![BU of 5ihl by Molmil](/molmil-images/mine/5ihl) | |
7BO6
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![BU of 7bo6 by Molmil](/molmil-images/mine/7bo6) | VDR complex with LCA derivative | 分子名称: | (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-(2-methyl-2-oxidanyl-propyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid, Nuclear receptor coactivator 1, Vitamin D3 receptor A | 著者 | Rochel, N. | 登録日 | 2021-01-24 | 公開日 | 2021-08-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Lithocholic acid-based design of noncalcemic vitamin D receptor agonists. Bioorg.Chem., 111, 2021
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5DMJ
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![BU of 5dmj by Molmil](/molmil-images/mine/5dmj) | |
6DFI
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![BU of 6dfi by Molmil](/molmil-images/mine/6dfi) | |
6DFJ
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![BU of 6dfj by Molmil](/molmil-images/mine/6dfj) | |