6RJG
Cryo-EM structure of St1Cas9-sgRNA-AcrIIA6-tDNA59-ntPAM complex.
Summary for 6RJG
Entry DOI | 10.2210/pdb6rjg/pdb |
Related | 6RJ9 6RJA 6RJD |
EMDB information | 4900 4901 4902 4904 |
Descriptor | AcrIIA6, Cas 9, sgRNA, ... (5 entities in total) |
Functional Keywords | crispr-cas9, anti-crispr protein, bacteriophages, streptococcus thermophilus cas9, st1cas9, hydrolase |
Biological source | Streptococcus phage D1811 More |
Total number of polymer chains | 6 |
Total formula weight | 235313.05 |
Authors | Goulet, A.,Chaves-Sanjuan, A.,Cambillau, C. (deposition date: 2019-04-26, release date: 2019-10-02, Last modification date: 2024-05-22) |
Primary citation | Fuchsbauer, O.,Swuec, P.,Zimberger, C.,Amigues, B.,Levesque, S.,Agudelo, D.,Duringer, A.,Chaves-Sanjuan, A.,Spinelli, S.,Rousseau, G.M.,Velimirovic, M.,Bolognesi, M.,Roussel, A.,Cambillau, C.,Moineau, S.,Doyon, Y.,Goulet, A. Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6. Mol.Cell, 76:922-, 2019 Cited by PubMed: 31604602DOI: 10.1016/j.molcel.2019.09.012 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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