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8BUX

Rab-binding domain of human MiniBAR

Summary for 8BUX
Entry DOI10.2210/pdb8bux/pdb
DescriptorGranule associated Rac and RHOG effector protein 1, 1,2-ETHANEDIOL, MALONATE ION, ... (5 entities in total)
Functional Keywordsrac effector, rab effector, protein transport
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight36891.16
Authors
Pylypenko, O.,Hammich, H.,Houdusse, A. (deposition date: 2022-12-01, release date: 2023-12-13)
Primary citationShaughnessy, R.,Serres, M.,Escot, S.,Hammich, H.,Cuvelier, F.,Rocancourt, M.,Verdon, Q.,Gaffuri, A.,Sourigues, Y.,Malherbe, G.,Velikovsky, L.,Chardon, F.,Thinevez, J.,Callebaut, I.,Formstecher, E.,Houdusse, A.,David, N.,Pylypenko, O.,Echard, A.
MiniBAR/KIAA0355 is a dual Rac and Rab effector that controls actin contractility and trafficking for successful ciliogenesis
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.86 Å)
Structure validation

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