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5DMJ

Structure of the extracellular domain of the CD40 in complex with 3H56-5 DAB

Summary for 5DMJ
Entry DOI10.2210/pdb5dmj/pdb
Related5DMI
DescriptorTumor necrosis factor receptor superfamily member 5, 3H65-5 domain antibody (dAb), POTASSIUM ION, ... (4 entities in total)
Functional Keywordscell surface receptor, domain antibody, protein/protein interaction, immune system-signaling protein complex, immune system/signaling protein
Biological sourceHomo sapiens (Human)
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Cellular locationIsoform I: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted: P25942
Total number of polymer chains6
Total formula weight100189.06
Authors
Sheriff, S. (deposition date: 2015-09-08, release date: 2016-06-01, Last modification date: 2023-09-27)
Primary citationYamniuk, A.P.,Suri, A.,Krystek, S.R.,Tamura, J.,Ramamurthy, V.,Kuhn, R.,Carroll, K.,Fleener, C.,Ryseck, R.,Cheng, L.,An, Y.,Drew, P.,Grant, S.,Suchard, S.J.,Nadler, S.G.,Bryson, J.W.,Sheriff, S.
Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
J.Mol.Biol., 428:2860-2879, 2016
Cited by
PubMed: 27216500
DOI: 10.1016/j.jmb.2016.05.014
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.79 Å)
Structure validation

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