5DMJ
Structure of the extracellular domain of the CD40 in complex with 3H56-5 DAB
Summary for 5DMJ
Entry DOI | 10.2210/pdb5dmj/pdb |
Related | 5DMI |
Descriptor | Tumor necrosis factor receptor superfamily member 5, 3H65-5 domain antibody (dAb), POTASSIUM ION, ... (4 entities in total) |
Functional Keywords | cell surface receptor, domain antibody, protein/protein interaction, immune system-signaling protein complex, immune system/signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform I: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted: P25942 |
Total number of polymer chains | 6 |
Total formula weight | 100189.06 |
Authors | Sheriff, S. (deposition date: 2015-09-08, release date: 2016-06-01, Last modification date: 2023-09-27) |
Primary citation | Yamniuk, A.P.,Suri, A.,Krystek, S.R.,Tamura, J.,Ramamurthy, V.,Kuhn, R.,Carroll, K.,Fleener, C.,Ryseck, R.,Cheng, L.,An, Y.,Drew, P.,Grant, S.,Suchard, S.J.,Nadler, S.G.,Bryson, J.W.,Sheriff, S. Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope. J.Mol.Biol., 428:2860-2879, 2016 Cited by PubMed: 27216500DOI: 10.1016/j.jmb.2016.05.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.79 Å) |
Structure validation
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