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8EHW
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BU of 8ehw by Molmil
cryo-EM structure of TMEM63A in nanodisc
分子名称: CSC1-like protein 1
著者Zheng, W, Fu, T.M, Holt, J.R.
登録日2022-09-14
公開日2023-08-23
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels.
Neuron, 111, 2023
8EHX
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BU of 8ehx by Molmil
cryo-EM structure of TMEM63B in LMNG
分子名称: CSC1-like protein 2
著者Zheng, W, Fu, T.M, Holt, J.R.
登録日2022-09-14
公開日2023-08-23
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels.
Neuron, 111, 2023
8P1U
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BU of 8p1u by Molmil
Structure of divisome complex FtsWIQLB
分子名称: Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ, ...
著者Yang, L, Chang, S, Tang, D, Dong, H.
登録日2023-05-12
公開日2024-05-22
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the activation of the divisome complex FtsWIQLB.
Cell Discov, 10, 2024
6K8K
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BU of 6k8k by Molmil
Crystal structure of Arabidopsis thaliana BIC2-CRY2 complex
分子名称: ADENOSINE MONOPHOSPHATE, Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Wang, X, Ma, L, Guan, Z, Yin, P.
登録日2019-06-12
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2.
Nat.Struct.Mol.Biol., 27, 2020
6K8I
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BU of 6k8i by Molmil
Crystal structure of Arabidopsis thaliana CRY2
分子名称: Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE
著者Ma, L, Wang, X, Guan, Z, Yin, P.
登録日2019-06-12
公開日2020-05-13
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2.
Nat.Struct.Mol.Biol., 27, 2020
7U6R
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BU of 7u6r by Molmil
Cryo-EM structure of PDF-2180 Spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PDF-2180 Spike glycoprotein
著者Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-03-05
公開日2022-11-30
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Close relatives of MERS-CoV in bats use ACE2 as their functional receptors.
Nature, 612, 2022
2GM1
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BU of 2gm1 by Molmil
Crystal structure of the mitotic kinesin eg5 in complex with mg-adp and n-(3-aminopropyl)-n-((3-benzyl-5-chloro-4-oxo-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)(cyclopropyl)methyl)-4-methylbenzamide
分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN-RELATED MOTOR PROTEIN EG5, MAGNESIUM ION, ...
著者Sheriff, S.
登録日2006-04-05
公開日2006-06-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Synthesis and SAR of pyrrolotriazine-4-one based Eg5 inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
5CDM
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BU of 5cdm by Molmil
2.5A structure of QPT-1 with S.aureus DNA gyrase and DNA
分子名称: (2R,4S,4aS)-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4',6'(1'H,3'H)-trione, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP*C*GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*T)-3'), DNA gyrase subunit A, ...
著者Bax, B.D, Srikannathasan, V, Chan, P.F.
登録日2015-07-04
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015
5CDN
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BU of 5cdn by Molmil
2.8A structure of etoposide with S.aureus DNA gyrase and DNA
分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP**GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP*C*GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*C)-3'), ...
著者Bax, B.D, Srikannathasan, V, Chan, P.F.
登録日2015-07-04
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015
5CDQ
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BU of 5cdq by Molmil
2.95A structure of Moxifloxacin with S.aureus DNA gyrase and DNA
分子名称: 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP*T*GP*GP*CP*CP*AP*TP*AP*CP*GP*CP*TP*T)-3'), DNA gyrase subunit A, ...
著者Bax, B.D, Srikannathasan, V, Chan, P.F.
登録日2015-07-04
公開日2015-12-16
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015
5CDP
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BU of 5cdp by Molmil
2.45A structure of etoposide with S.aureus DNA gyrase and DNA
分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*G*GP*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), DNA gyrase subunit A, ...
著者Bax, B.D, Srikannathasan, V, Chan, P.F.
登録日2015-07-04
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015
5CDO
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BU of 5cdo by Molmil
3.15A structure of QPT-1 with S.aureus DNA gyrase and DNA
分子名称: (2R,4S,4aS)-4',6'-dihydroxy-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidin]-2'-one, (2R,4S,4aS,5R)-6'-hydroxy-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4'(3'H)-dione, (2R,4S,4aS,5S)-6'-hydroxy-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4'(3'H)-dione, ...
著者Bax, B.D, Srikannathasan, V, Chan, P.F.
登録日2015-07-04
公開日2015-12-16
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015
5CDR
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BU of 5cdr by Molmil
2.65 structure of S.aureus DNA gyrase and artificially nicked DNA
分子名称: DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*)-3'), DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), DNA (5'-D(*GP*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ...
著者Bax, B.D, Srikannathasan, V, Chan, P.F.
登録日2015-07-04
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun, 6, 2015
5YHQ
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BU of 5yhq by Molmil
Cryo-EM Structure of CVA6 VLP
分子名称: Capsid protein VP1, Capsid protein VP3, capsid protein VP0
著者Chen, J, Zhang, C, Huang, Z, Cong, Y.
登録日2017-09-29
公開日2017-10-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A 3.0-Angstrom Resolution Cryo-Electron Microscopy Structure and Antigenic Sites of Coxsackievirus A6-Like Particles.
J. Virol., 92, 2018
6EF8
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BU of 6ef8 by Molmil
Cryo-EM of the OmcS nanowires from Geobacter sulfurreducens
分子名称: C-type cytochrome OmcS, HEME C
著者Wang, F, Gu, Y, Egelman, E.H, Malvankar, N.S.
登録日2018-08-16
公開日2019-04-10
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of Microbial Nanowires Reveals Stacked Hemes that Transport Electrons over Micrometers.
Cell, 177, 2019
3HPK
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BU of 3hpk by Molmil
Oxidized dimeric PICK1 PDZ in complex with the carboxyl tail peptide of GluR2
分子名称: GLYCEROL, PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT
著者Yu, J, Shi, Y, Zhang, M.
登録日2009-06-04
公開日2010-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain.
Biochemistry, 49, 2010
3HPM
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BU of 3hpm by Molmil
Oxidized dimeric PICK1 PDZ C46G mutant in complex with the carboxyl tail peptide of GluR2
分子名称: PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT
著者Yu, J, Shi, Y, Zhang, M.
登録日2009-06-04
公開日2010-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain.
Biochemistry, 49, 2010
6BFN
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BU of 6bfn by Molmil
Crystal structure of human IRAK1
分子名称: Interleukin-1 receptor-associated kinase 1, N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide
著者Wang, L, Qiao, Q, Wu, H.
登録日2017-10-26
公開日2017-12-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal structure of human IRAK1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2ND0
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BU of 2nd0 by Molmil
Solution NMR structures of BRD4 ET domain with LANA peptide
分子名称: Bromodomain-containing protein 4, LANA
著者Zeng, L, Zhou, M.
登録日2016-04-18
公開日2016-06-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
Structure, 24, 2016
2NCZ
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BU of 2ncz by Molmil
Solution NMR structures of BRD4 ET domain in complex with NSD3_1 peptide
分子名称: Bromodomain-containing protein 4, Histone-lysine N-methyltransferase NSD3
著者Zeng, L, Zhou, M.
登録日2016-04-18
公開日2016-06-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
Structure, 24, 2016
2ND1
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BU of 2nd1 by Molmil
Solution NMR structures of BRD4 ET domain in complex with NSD3_3 peptide
分子名称: Bromodomain-containing protein 4, Histone-lysine N-methyltransferase NSD3
著者Zeng, L, Zhou, M.
登録日2016-04-19
公開日2016-06-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
Structure, 24, 2016
9EQG
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BU of 9eqg by Molmil
CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with GABA and puerarin
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kasaragod, V.B, Aricescu, A.R.
登録日2024-03-21
公開日2024-09-18
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献A brain-to-gut signal controls intestinal fat absorption.
Nature, 2024
5XJS
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BU of 5xjs by Molmil
Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with SmD1(1-82)/D2/F/E from Human
分子名称: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
著者Yi, H, Zhang, R.
登録日2017-05-04
公開日2018-07-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly.
Nucleic Acids Res., 2019
5XJR
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BU of 5xjr by Molmil
Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with SmD1(1-82)/D2/F/E/G from Human
分子名称: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
著者Yi, H, Zhang, R.
登録日2017-05-04
公開日2018-07-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly.
Nucleic Acids Res., 2019
8TBP
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BU of 8tbp by Molmil
HLA-DRB1*15:01 in complex with smith antigen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Ting, Y.T, Broury, A, Ooi, J.
登録日2023-06-29
公開日2024-02-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.12621117 Å)
主引用文献Smith-specific regulatory T cells halt the progression of lupus nephritis.
Nat Commun, 15, 2024

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