5XJR

Crystal Structure of the Gemin2-binding domain of SMN, Gemin2dN39 in Complex with SmD1(1-82)/D2/F/E/G from Human

Summary for 5XJR

• Entry DOI: 10.2210/pdb5xjr/pdb
• Related: 5XJL 5XJQ 5XJS
• Descriptor: Gem-associated protein 2, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, ... (7 entities in total)
• Functional Keywords: splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 7
• Total formula weight: 83283.17

Authors

Yi, H.,Zhang, R. (deposition date: 2017-05-04, release date: 2018-07-04, Last modification date: 2023-11-22)

• Primary citation: Yi, H.,Mu, L.,Shen, C.,Kong, X.,Wang, Y.,Hou, Y.,Zhang, R.; Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly.; Nucleic Acids Res., 2019; PubMed: 31799625; DOI: 10.1093/nar/gkz1135

Experimental method

X-RAY DIFFRACTION (3.12 Å)