8EHX

cryo-EM structure of TMEM63B in LMNG

Summary for 8EHX

Entry DOI	10.2210/pdb8ehx/pdb
EMDB information	28154
Descriptor	CSC1-like protein 2 (1 entity in total)
Functional Keywords	ion channel, mechanosensitive, monomeric, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	96051.20
Authors	Zheng, W.,Fu, T.M.,Holt, J.R. (deposition date: 2022-09-14, release date: 2023-08-23, Last modification date: 2023-11-01)
Primary citation	Zheng, W.,Rawson, S.,Shen, Z.,Tamilselvan, E.,Smith, H.E.,Halford, J.,Shen, C.,Murthy, S.E.,Ulbrich, M.H.,Sotomayor, M.,Fu, T.M.,Holt, J.R. TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels. Neuron, 111:3195-, 2023 Cited by PubMed: 37543036 DOI: 10.1016/j.neuron.2023.07.006 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation