5CDR
2.65 structure of S.aureus DNA gyrase and artificially nicked DNA
Summary for 5CDR
Entry DOI | 10.2210/pdb5cdr/pdb |
Descriptor | DNA gyrase subunit A, DNA gyrase subunit B,DNA gyrase subunit B, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*)-3'), ... (8 entities in total) |
Functional Keywords | type iia topoisomerase, isomerase |
Biological source | Staphylococcus aureus (strain N315) More |
Cellular location | Cytoplasm : Q99XG5 P66937 |
Total number of polymer chains | 7 |
Total formula weight | 165439.01 |
Authors | Bax, B.D.,Srikannathasan, V.,Chan, P.F. (deposition date: 2015-07-04, release date: 2015-12-16, Last modification date: 2024-01-10) |
Primary citation | Chan, P.F.,Srikannathasan, V.,Huang, J.,Cui, H.,Fosberry, A.P.,Gu, M.,Hann, M.M.,Hibbs, M.,Homes, P.,Ingraham, K.,Pizzollo, J.,Shen, C.,Shillings, A.J.,Spitzfaden, C.E.,Tanner, R.,Theobald, A.J.,Stavenger, R.A.,Bax, B.D.,Gwynn, M.N. Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin. Nat Commun, 6:10048-10048, 2015 Cited by PubMed: 26640131DOI: 10.1038/ncomms10048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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