Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006265 | biological_process | DNA topological change |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006259 | biological_process | DNA metabolic process |
| C | 0006265 | biological_process | DNA topological change |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 501 |
| Chain | Residue |
| A | TYR322 |
| A | THR325 |
| A | GLN328 |
| A | HOH705 |
| A | HOH809 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | ASP61 |
| A | ARG127 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | PRO219 |
| A | THR220 |
| A | ASP96 |
| A | MET113 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 701 |
| Chain | Residue |
| B | ASP508 |
| B | ASP510 |
| B | HOH818 |
| B | HOH842 |
| B | HOH848 |
| E | HOH211 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 501 |
| Chain | Residue |
| C | ARG47 |
| C | ARG48 |
| C | GLU156 |
| C | PRO157 |
| C | HOH612 |
| C | HOH677 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 502 |
| Chain | Residue |
| A | ARG244 |
| A | ASN319 |
| C | GLU251 |
| C | GLY255 |
| C | ARG256 |
| C | HOH686 |
| C | HOH709 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MN D 1001 |
| Chain | Residue |
| D | ASP508 |
| D | ASP510 |
| D | HOH1108 |
| D | HOH1110 |
| D | HOH1116 |
| D | HOH1130 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL E 101 |
| Chain | Residue |
| A | PHE97 |
| A | SER112 |
| A | MET113 |
| A | GLN267 |
| A | VAL268 |
| A | HOH681 |
| E | DC4 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL G 2101 |
| Chain | Residue |
| A | SER84 |
| E | DG8 |
| F | DC2013 |
| G | DG2009 |
| G | DT2010 |
| G | HOH2213 |
Functional Information from PROSITE/UniProt
| site_id | PS00177 |
| Number of Residues | 9 |
| Details | TOPOISOMERASE_II DNA topoisomerase II signature. LVEGDSAGG |
| Chain | Residue | Details |
| B | LEU433-GLY441 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | GLU435 | |
| B | ASP508 | |
| B | ASP510 | |
| D | GLU435 | |
| D | ASP508 | |
| D | ASP510 | |
| Chain | Residue | Details |
| B | LYS460 | |
| B | ASN463 | |
| D | LYS460 | |
| D | ASN463 | |
