8EBZ
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8EPW
| Crystal Structure of KRAS4b-G13D (GMPPNP-bound) in complex with RAS-binding domain (RBD) of RAF1/CRAF | 分子名称: | GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K. | 登録日 | 2022-10-06 | 公開日 | 2023-06-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Reduced dynamic complexity allows structure elucidation of an excited state of KRAS G13D . Commun Biol, 6, 2023
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8FTQ
| Crystal structure of hRpn13 Pru domain in complex with Ubiquitin and XL44 | 分子名称: | N-(3-{[(3R)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl]methyl}phenyl)-4-methoxybenzamide, Proteasomal ubiquitin receptor ADRM1, Ubiquitin | 著者 | Walters, K.J, Lu, X, Chandravanshi, M. | 登録日 | 2023-01-13 | 公開日 | 2024-03-27 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nat Commun, 15, 2024
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2V93
| EQUILLIBRIUM MIXTURE OF OPEN AND PARTIALLY-CLOSED SPECIES IN THE APO STATE OF MALTODEXTRIN-BINDING PROTEIN BY PARAMAGNETIC RELAXATION ENHANCEMENT NMR | 分子名称: | 1-(1-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL)PYRROLIDINE-2,5-DIONE, MALTOSE-BINDING PERIPLASMIC PROTEIN | 著者 | Clore, G.M, Tang, C. | 登録日 | 2007-08-21 | 公開日 | 2007-11-06 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Open-to-Closed Transition in Apo Maltose-Binding Protein Observed by Paramagnetic NMR. Nature, 449, 2007
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6UUQ
| Structure of Calcineurin bound to RCAN1 | 分子名称: | Calcipressin-1, FE (III) ION, PHOSPHATE ION, ... | 著者 | Sheftic, S, Page, R, Peti, W. | 登録日 | 2019-10-31 | 公開日 | 2020-09-09 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (1.849 Å) | 主引用文献 | The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin. Sci Adv, 6, 2020
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7KXI
| Structure of XL5-ligated hRpn13 Pru domain | 分子名称: | 2-{[(2S)-2-cyano-3-{3-[(4-methylbenzene-1-carbonyl)amino]phenyl}propanoyl]amino}benzoic acid, Proteasomal ubiquitin receptor ADRM1 | 著者 | Lu, X, Walters, K.J. | 登録日 | 2020-12-03 | 公開日 | 2021-12-15 | 最終更新日 | 2021-12-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma. Nat Commun, 12, 2021
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2KLJ
| Solution Structure of gammaD-Crystallin with RDC and SAXS | 分子名称: | Gamma-crystallin D | 著者 | Wang, J, Zuo, X, Yu, P, Byeon, I, Jung, J, Gronenborn, A.M, Wang, Y. | 登録日 | 2009-07-06 | 公開日 | 2009-10-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR, SOLUTION SCATTERING | 主引用文献 | Determination of multicomponent protein structures in solution using global orientation and shape restraints. J.Am.Chem.Soc., 131, 2009
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2KRL
| The ensemble of the solution global structures of the 102-nt ribosome binding structure element of the turnip crinkle virus 3' UTR RNA | 分子名称: | RNA (102-MER) | 著者 | Zuo, X, Wang, J, Yu, P, Eyler, D, Xu, H, Starich, M, Tiede, D, Simon, A, Kasprzak, W, Schwieters, C, Shapiro, B. | 登録日 | 2009-12-18 | 公開日 | 2011-02-09 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR, SOLUTION SCATTERING | 主引用文献 | Solution structure of the cap-independent translational enhancer and ribosome-binding element in the 3' UTR of turnip crinkle virus. Proc.Natl.Acad.Sci.USA, 107, 2010
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2M4J
| 40-residue beta-amyloid fibril derived from Alzheimer's disease brain | 分子名称: | Amyloid beta A4 protein | 著者 | Lu, J, Qiang, W, Meredith, S.C, Yau, W, Schweiters, C.D, Tycko, R. | 登録日 | 2013-02-05 | 公開日 | 2013-09-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Molecular Structure of beta-Amyloid Fibrils in Alzheimer's Disease Brain Tissue. Cell(Cambridge,Mass.), 154, 2013
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2JYJ
| Re-refining the tetraloop-receptor RNA-RNA complex using NMR-derived restraints and Xplor-nih (2.18) | 分子名称: | RNA (43-MER) | 著者 | Zuo, X, Wang, J, Foster, T.R, Schwieters, C.D, Tiede, D.M, Butcher, S.E, Wang, Y. | 登録日 | 2007-12-13 | 公開日 | 2008-10-07 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | RNA helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex. J.Mol.Biol., 351, 2005
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2H8W
| Solution structure of ribosomal protein L11 | 分子名称: | 50S ribosomal protein L11 | 著者 | Lee, D, Walsh, J.D, Yu, P, Choli-Papadopoulou, T, Krueger, S, Draper, D, Wang, Y.-X. | 登録日 | 2006-06-08 | 公開日 | 2007-02-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | The Structure of Free L11 and Functional Dynamics of L11 in Free, L11-rRNA(58 nt) Binary and L11-rRNA(58 nt)-thiostrepton Ternary Complexes. J.Mol.Biol., 367, 2007
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2N2M
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2N74
| Solution Structure of the RNA-Binding domain of non-structural protein 1 from the 1918 H1N1 influenza virus | 分子名称: | Non-structural protein 1 | 著者 | Jureka, A.S, Kleinpeter, A.B, Cornilescu, G, Cornilescu, C.C, Schwieters, C.D, Petit, C.M. | 登録日 | 2015-09-03 | 公開日 | 2015-09-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I. Structure, 23, 2015
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