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8EBZ
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BU of 8ebz by Molmil
Crystal Structure of GMPPNP-bound KRAS-G13D mutant at 1.2 Ang resolution
分子名称: Isoform 2B of GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Chan, A.H, Simanshu, D.K.
登録日2022-08-31
公開日2023-06-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Reduced dynamic complexity allows structure elucidation of an excited state of KRAS G13D .
Commun Biol, 6, 2023
8EPW
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BU of 8epw by Molmil
Crystal Structure of KRAS4b-G13D (GMPPNP-bound) in complex with RAS-binding domain (RBD) of RAF1/CRAF
分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Tran, T.H, Chan, A.H, Dharmaiah, S, Simanshu, D.K.
登録日2022-10-06
公開日2023-06-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reduced dynamic complexity allows structure elucidation of an excited state of KRAS G13D .
Commun Biol, 6, 2023
8FTQ
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BU of 8ftq by Molmil
Crystal structure of hRpn13 Pru domain in complex with Ubiquitin and XL44
分子名称: N-(3-{[(3R)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl]methyl}phenyl)-4-methoxybenzamide, Proteasomal ubiquitin receptor ADRM1, Ubiquitin
著者Walters, K.J, Lu, X, Chandravanshi, M.
登録日2023-01-13
公開日2024-03-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins.
Nat Commun, 15, 2024
2V93
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BU of 2v93 by Molmil
EQUILLIBRIUM MIXTURE OF OPEN AND PARTIALLY-CLOSED SPECIES IN THE APO STATE OF MALTODEXTRIN-BINDING PROTEIN BY PARAMAGNETIC RELAXATION ENHANCEMENT NMR
分子名称: 1-(1-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL)PYRROLIDINE-2,5-DIONE, MALTOSE-BINDING PERIPLASMIC PROTEIN
著者Clore, G.M, Tang, C.
登録日2007-08-21
公開日2007-11-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Open-to-Closed Transition in Apo Maltose-Binding Protein Observed by Paramagnetic NMR.
Nature, 449, 2007
6UUQ
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BU of 6uuq by Molmil
Structure of Calcineurin bound to RCAN1
分子名称: Calcipressin-1, FE (III) ION, PHOSPHATE ION, ...
著者Sheftic, S, Page, R, Peti, W.
登録日2019-10-31
公開日2020-09-09
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin.
Sci Adv, 6, 2020
7KXI
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BU of 7kxi by Molmil
Structure of XL5-ligated hRpn13 Pru domain
分子名称: 2-{[(2S)-2-cyano-3-{3-[(4-methylbenzene-1-carbonyl)amino]phenyl}propanoyl]amino}benzoic acid, Proteasomal ubiquitin receptor ADRM1
著者Lu, X, Walters, K.J.
登録日2020-12-03
公開日2021-12-15
最終更新日2021-12-29
実験手法SOLUTION NMR
主引用文献Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma.
Nat Commun, 12, 2021
2KLJ
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BU of 2klj by Molmil
Solution Structure of gammaD-Crystallin with RDC and SAXS
分子名称: Gamma-crystallin D
著者Wang, J, Zuo, X, Yu, P, Byeon, I, Jung, J, Gronenborn, A.M, Wang, Y.
登録日2009-07-06
公開日2009-10-06
最終更新日2024-05-22
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Determination of multicomponent protein structures in solution using global orientation and shape restraints.
J.Am.Chem.Soc., 131, 2009
2KRL
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BU of 2krl by Molmil
The ensemble of the solution global structures of the 102-nt ribosome binding structure element of the turnip crinkle virus 3' UTR RNA
分子名称: RNA (102-MER)
著者Zuo, X, Wang, J, Yu, P, Eyler, D, Xu, H, Starich, M, Tiede, D, Simon, A, Kasprzak, W, Schwieters, C, Shapiro, B.
登録日2009-12-18
公開日2011-02-09
最終更新日2024-05-01
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Solution structure of the cap-independent translational enhancer and ribosome-binding element in the 3' UTR of turnip crinkle virus.
Proc.Natl.Acad.Sci.USA, 107, 2010
2M4J
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BU of 2m4j by Molmil
40-residue beta-amyloid fibril derived from Alzheimer's disease brain
分子名称: Amyloid beta A4 protein
著者Lu, J, Qiang, W, Meredith, S.C, Yau, W, Schweiters, C.D, Tycko, R.
登録日2013-02-05
公開日2013-09-25
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Molecular Structure of beta-Amyloid Fibrils in Alzheimer's Disease Brain Tissue.
Cell(Cambridge,Mass.), 154, 2013
2JYJ
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BU of 2jyj by Molmil
Re-refining the tetraloop-receptor RNA-RNA complex using NMR-derived restraints and Xplor-nih (2.18)
分子名称: RNA (43-MER)
著者Zuo, X, Wang, J, Foster, T.R, Schwieters, C.D, Tiede, D.M, Butcher, S.E, Wang, Y.
登録日2007-12-13
公開日2008-10-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献RNA helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex.
J.Mol.Biol., 351, 2005
2H8W
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BU of 2h8w by Molmil
Solution structure of ribosomal protein L11
分子名称: 50S ribosomal protein L11
著者Lee, D, Walsh, J.D, Yu, P, Choli-Papadopoulou, T, Krueger, S, Draper, D, Wang, Y.-X.
登録日2006-06-08
公開日2007-02-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The Structure of Free L11 and Functional Dynamics of L11 in Free, L11-rRNA(58 nt) Binary and L11-rRNA(58 nt)-thiostrepton Ternary Complexes.
J.Mol.Biol., 367, 2007
2N2M
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BU of 2n2m by Molmil
NMR structure of yersinia pestis Ail (attachment invasion locus) in decylphosphocholine micelles
分子名称: Outer membrane protein X
著者Marassi, F.M, Ding, Y, Yao, Y.
登録日2015-05-10
公開日2015-07-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Backbone structure of Yersinia pestis Ail determined in micelles by NMR-restrained simulated annealing with implicit membrane solvation.
J.Biomol.Nmr, 63, 2015
2N74
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BU of 2n74 by Molmil
Solution Structure of the RNA-Binding domain of non-structural protein 1 from the 1918 H1N1 influenza virus
分子名称: Non-structural protein 1
著者Jureka, A.S, Kleinpeter, A.B, Cornilescu, G, Cornilescu, C.C, Schwieters, C.D, Petit, C.M.
登録日2015-09-03
公開日2015-09-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for a Novel Interaction between the NS1 Protein Derived from the 1918 Influenza Virus and RIG-I.
Structure, 23, 2015
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