6UUQ

Structure of Calcineurin bound to RCAN1

Summary for 6UUQ

Entry DOI	10.2210/pdb6uuq/pdb
Descriptor	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcipressin-1, PHOSPHATE ION, ... (6 entities in total)
Functional Keywords	ser/thr phosphatase, hydrolase, hydrolase-signaling protein complex, hydrolase/signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	41122.71
Authors	Sheftic, S.,Page, R.,Peti, W. (deposition date: 2019-10-31, release date: 2020-09-09, Last modification date: 2023-10-11)
Primary citation	Li, Y.,Sheftic, S.R.,Grigoriu, S.,Schwieters, C.D.,Page, R.,Peti, W. The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin. Sci Adv, 6:-, 2020 Cited by PubMed: 32936779 DOI: 10.1126/sciadv.aba3681 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.849 Å)

Structure validation