7DDN
 
 | | SARS-Cov2 S protein at open state | | 分子名称: | Spike glycoprotein | | 著者 | Cong, Y, Liu, C.X. | | 登録日 | 2020-10-29 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | | 主引用文献 | Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
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7DDD
 | | SARS-Cov2 S protein at close state | | 分子名称: | Spike glycoprotein | | 著者 | Cong, Y, Liu, C.X. | | 登録日 | 2020-10-28 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.
Nat Commun, 12, 2021
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7DCX
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7DK7
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7DCC
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7DD8
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7DK5
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7DK6
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7DF4
 | | SARS-CoV-2 S-ACE2 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Cong, X, Yao, C. | | 登録日 | 2020-11-06 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM.
Sci Adv, 7, 2021
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7DF3
 | | SARS-CoV-2 S trimer, S-closed | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Cong, X, Yao, C. | | 登録日 | 2020-11-06 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM.
Sci Adv, 7, 2021
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7DK3
 | | SARS-CoV-2 S trimer, S-open | | 分子名称: | Spike glycoprotein | | 著者 | Xu, C, Cong, Y. | | 登録日 | 2020-11-23 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM.
Sci Adv, 7, 2021
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8K4F
 | | DHODH in complex with compound A0 | | 分子名称: | 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine, 6-[bis(oxidanyl)methyl]-5~{H}-pyrimidine-2,4-dione, ACETATE ION, ... | | 著者 | Jian, L, Sun, Q. | | 登録日 | 2023-07-18 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Discovery and Optimization of Novel h DHODH Inhibitors for the Treatment of Inflammatory Bowel Disease.
J.Med.Chem., 66, 2023
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8H0Z
 | | Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-122 Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | 著者 | Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X. | | 登録日 | 2022-09-30 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | | 主引用文献 | Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes.
Life Sci Alliance, 6, 2023
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8TNB
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8TNC
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8TN1
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8TND
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8TN6
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7SRS
 | | 5-HT2B receptor bound to LSD in complex with beta-arrestin1 obtained by cryo-electron microscopy (cryoEM) | | 分子名称: | (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 2B, ... | | 著者 | Barros-Alvarez, X, Cao, C, Panova, O, Roth, B.L, Skiniotis, G. | | 登録日 | 2021-11-08 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Neuron, 110, 2022
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7SRQ
 | | 5-HT2B receptor bound to LSD obtained by cryo-electron microscopy (cryoEM) | | 分子名称: | (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 2B | | 著者 | Barros-Alvarez, X, Cao, C, Panova, O, Roth, B.L, Skiniotis, G. | | 登録日 | 2021-11-08 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Neuron, 110, 2022
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7SRR
 | | 5-HT2B receptor bound to LSD in complex with heterotrimeric mini-Gq protein obtained by cryo-electron microscopy (cryoEM) | | 分子名称: | (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, 5-hydroxytryptamine receptor 2B, G protein subunit q (Gi2-mini-Gq chimera), ... | | 著者 | Barros-Alvarez, X, Kim, K, Panova, O, Cao, C, Roth, B.L, Skiniotis, G. | | 登録日 | 2021-11-08 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Neuron, 110, 2022
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5Z8N
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5Z8L
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2RJP
 | | Crystal structure of ADAMTS4 with inhibitor bound | | 分子名称: | ADAMTS-4, CALCIUM ION, N-({4'-[(4-isobutyrylphenoxy)methyl]biphenyl-4-yl}sulfonyl)-D-valine, ... | | 著者 | Mosyak, L, Stahl, M, Somers, W. | | 登録日 | 2007-10-15 | | 公開日 | 2007-12-11 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Protein Sci., 17, 2008
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2RJQ
 | | Crystal structure of ADAMTS5 with inhibitor bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, ADAMTS-5, ... | | 著者 | Mosyak, L, Stahl, M, Somers, W. | | 登録日 | 2007-10-15 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Protein Sci., 17, 2008
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