7DK6

S-2H2-F2 structure, two RBDs are up and one RBD is down, each up RBD binds with a 2H2 Fab.

Summary for 7DK6

• Entry DOI: 10.2210/pdb7dk6/pdb
• EMDB information: 30704
• Descriptor: Spike glycoprotein, The heavy chain of 2H2 Fab, The light chain of 2H2 Fab (3 entities in total)
• Functional Keywords: viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 7
• Total formula weight: 513763.55

Authors

Cong, Y.,Wang, Y.F. (deposition date: 2020-11-23, release date: 2020-12-02, Last modification date: 2021-03-10)

• Primary citation: Zhang, C.,Wang, Y.,Zhu, Y.,Liu, C.,Gu, C.,Xu, S.,Wang, Y.,Zhou, Y.,Wang, Y.,Han, W.,Hong, X.,Yang, Y.,Zhang, X.,Wang, T.,Xu, C.,Hong, Q.,Wang, S.,Zhao, Q.,Qiao, W.,Zang, J.,Kong, L.,Wang, F.,Wang, H.,Qu, D.,Lavillette, D.,Tang, H.,Deng, Q.,Xie, Y.,Cong, Y.,Huang, Z.; Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections.; Nat Commun, 12:264-264, 2021; PubMed: 33431876; DOI: 10.1038/s41467-020-20465-w

Experimental method

ELECTRON MICROSCOPY (4.3 Å)