7PGU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pgu by Molmil](/molmil-images/mine/7pgu) | Autoinhibited structure of human neurofibromin isoform 2 stabilized by Zinc. | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Neurofibromin, ZINC ION | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | 登録日 | 2021-08-15 | 公開日 | 2021-11-17 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
|
|
7PGT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pgt by Molmil](/molmil-images/mine/7pgt) | The structure of human neurofibromin isoform 2 in opened conformation. | 分子名称: | Neurofibromin, ZINC ION | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | 登録日 | 2021-08-15 | 公開日 | 2021-11-17 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
|
|
7PGS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pgs by Molmil](/molmil-images/mine/7pgs) | Consensus structure of human Neurofibromin isoform 2 | 分子名称: | Neurofibromin, ZINC ION | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | 登録日 | 2021-08-15 | 公開日 | 2021-11-17 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
|
|
7PGR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pgr by Molmil](/molmil-images/mine/7pgr) | The structure of human neurofibromin isoform 2 in closed conformation | 分子名称: | Neurofibromin, ZINC ION | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | 登録日 | 2021-08-15 | 公開日 | 2021-11-17 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
|
|
7PGP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pgp by Molmil](/molmil-images/mine/7pgp) | |
7PGQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pgq by Molmil](/molmil-images/mine/7pgq) | GAP-SecPH region of human neurofibromin isoform 2 in closed conformation. | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Neurofibromin, ZINC ION | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | 登録日 | 2021-08-15 | 公開日 | 2022-10-26 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599, 2021
|
|
8PPV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ppv by Molmil](/molmil-images/mine/8ppv) | Intermediate conformer of Pyrococcus abyssi DNA polymerase D (PolD) bound to a primer/template substrate containing three consecutive mismatches | 分子名称: | DNA (5'-D(*P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(G7P)P*(PST)P*(PST)P*(PST))-3'), DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA polymerase II small subunit, ... | 著者 | Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. | 登録日 | 2023-07-10 | 公開日 | 2023-12-20 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases. Nat Commun, 14, 2023
|
|
8PPU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ppu by Molmil](/molmil-images/mine/8ppu) | Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing three consecutive mismatches | 分子名称: | DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(C7R)P*(PST)P*(PST)P*(PST))-3'), DNA polymerase II small subunit, ... | 著者 | Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. | 登録日 | 2023-07-10 | 公開日 | 2023-12-20 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases. Nat Commun, 14, 2023
|
|
8PPT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ppt by Molmil](/molmil-images/mine/8ppt) | Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing a mismatch | 分子名称: | DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*GP*CP*TP*TP*T)-3'), DNA polymerase II small subunit, ... | 著者 | Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. | 登録日 | 2023-07-10 | 公開日 | 2023-12-20 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases. Nat Commun, 14, 2023
|
|
6XZ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xz6 by Molmil](/molmil-images/mine/6xz6) | |
6ZGK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zgk by Molmil](/molmil-images/mine/6zgk) | GLIC pentameric ligand-gated ion channel, pH 3 | 分子名称: | Proton-gated ion channel | 著者 | Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E. | 登録日 | 2020-06-18 | 公開日 | 2021-05-26 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations. Life Sci Alliance, 4, 2021
|
|
6ZGD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zgd by Molmil](/molmil-images/mine/6zgd) | GLIC pentameric ligand-gated ion channel, pH 7 | 分子名称: | Proton-gated ion channel | 著者 | Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E. | 登録日 | 2020-06-18 | 公開日 | 2021-05-26 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations. Life Sci Alliance, 4, 2021
|
|
6ZGJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zgj by Molmil](/molmil-images/mine/6zgj) | GLIC pentameric ligand-gated ion channel, pH 5 | 分子名称: | Proton-gated ion channel | 著者 | Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E. | 登録日 | 2020-06-18 | 公開日 | 2021-05-26 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations. Life Sci Alliance, 4, 2021
|
|
6SOY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6soy by Molmil](/molmil-images/mine/6soy) | Trypanosoma brucei transferrin receptor in complex with human transferrin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, subunit of heterodimeric transferrin receptor, ... | 著者 | Trevor, C, Carrington, M, Higgins, M.K. | 登録日 | 2019-08-30 | 公開日 | 2019-11-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion. Nat Microbiol, 4, 2019
|
|
6SOZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6soz by Molmil](/molmil-images/mine/6soz) | Glycosylated Trypanosoma brucei transferrin receptor in complex with human transferrin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, ... | 著者 | Trevor, C, Carrington, M, Higgins, M.K. | 登録日 | 2019-08-30 | 公開日 | 2019-11-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion. Nat Microbiol, 4, 2019
|
|
6FU8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fu8 by Molmil](/molmil-images/mine/6fu8) | |
6FB3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fb3 by Molmil](/molmil-images/mine/6fb3) | Teneurin 2 Partial Extracellular Domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Teneurin-2, ... | 著者 | Jackson, V.A, Carrasquero, M, Lowe, E.D, Seiradake, E. | 登録日 | 2017-12-18 | 公開日 | 2018-03-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction. Nat Commun, 9, 2018
|
|
1XU6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xu6 by Molmil](/molmil-images/mine/1xu6) | Structure of the C-terminal domain from Trypanosoma brucei Variant Surface Glycoprotein MITat1.2 | 分子名称: | Variant surface glycoprotein MITAT 1.2 | 著者 | Chattopadhyay, A, Jones, N.G, Nietlispach, D, Nielsen, P.R, Voorheis, H.P, Mott, H.R, Carrington, M. | 登録日 | 2004-10-25 | 公開日 | 2004-11-30 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the C-terminal domain from Trypanosoma brucei variant surface glycoprotein MITat1.2 J.Biol.Chem., 280, 2004
|
|
3TTI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tti by Molmil](/molmil-images/mine/3tti) | Crystal Structure of JNK3 complexed with CC-930, an orally active anti-fibrotic JNK inhibitor | 分子名称: | GLYCEROL, Mitogen-activated protein kinase 10, trans-4-({9-[(3S)-tetrahydrofuran-3-yl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl}amino)cyclohexanol | 著者 | Plantevin-Krenitsky, V, Nadolny, L, Delgado, M, Ayala, L, Clareen, S, Hilgraf, R, Albers, R, Hegde, S, D'Sidocky, N, Sapienza, J, Wright, J, McCarrick, M, Bahmanyar, S, Chamberlain, P, Delker, S.L, Muir, J, Giegel, D, Xu, L, Celeridad, M, Lachowitzer, J, Bennett, B, Moghaddam, M, Khatsenko, O, Katz, J, Fan, R, Bai, A, Tang, Y, Shirley, M.A, Benish, B, Bodine, T, Blease, K, Raymon, H, Cathers, B.E, Satoh, Y. | 登録日 | 2011-09-14 | 公開日 | 2012-02-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor. Bioorg.Med.Chem.Lett., 22, 2012
|
|
2JWH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jwh by Molmil](/molmil-images/mine/2jwh) | Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein | 分子名称: | Variant surface glycoprotein ILTAT 1.24 | 著者 | Jones, N.G, Nietlispach, D, Sharma, R, Burke, D.F, Eyres, I, Mues, M, Mott, H.R, Carrington, M. | 登録日 | 2007-10-12 | 公開日 | 2007-11-13 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein J.Biol.Chem., 283, 2008
|
|
2JWG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jwg by Molmil](/molmil-images/mine/2jwg) | Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein | 分子名称: | Variant surface glycoprotein ILTAT 1.24 | 著者 | Jones, N.G, Nietlispach, D, Sharma, R, Burke, D.F, Eyres, I, Mues, M, Mott, H.R, Carrington, M. | 登録日 | 2007-10-12 | 公開日 | 2007-11-13 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein J.Biol.Chem., 283, 2008
|
|
3OLS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ols by Molmil](/molmil-images/mine/3ols) | Crystal structure of estrogen receptor beta ligand binding domain | 分子名称: | ESTRADIOL, Estrogen receptor beta, Nuclear receptor coactivator 1 | 著者 | Moecklinghoff, S, Rose, R, Carraz, M, Visser, A, Ottmann, C, Brunsveld, L. | 登録日 | 2010-08-26 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain. Chembiochem, 11, 2010
|
|
5OFO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ofo by Molmil](/molmil-images/mine/5ofo) | Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state, bound to the model substrate casein | 分子名称: | Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R. | 登録日 | 2017-07-11 | 公開日 | 2017-08-16 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase. Sci Adv, 3, 2017
|
|
5AFB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5afb by Molmil](/molmil-images/mine/5afb) | Crystal structure of the Latrophilin3 Lectin and Olfactomedin Domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | Jackson, V.A, del Toro, D, Carrasquero, M, Roversi, P, Harlos, K, Klein, R, Seiradake, E. | 登録日 | 2015-01-21 | 公開日 | 2015-03-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Structural Basis of Latrophilin-Flrt Interaction. Structure, 23, 2015
|
|
5OG1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5og1 by Molmil](/molmil-images/mine/5og1) | Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state | 分子名称: | Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Deville, C, Carroni, M, Franke, K.B, Topf, M, Bukau, B, Mogk, A, Saibil, H.R. | 登録日 | 2017-07-11 | 公開日 | 2017-08-16 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase. Sci Adv, 3, 2017
|
|