5OFO

Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state, bound to the model substrate casein

Summary for 5OFO

• Entry DOI: 10.2210/pdb5ofo/pdb
• Related: 5OG1
• EMDB information: 3776 3777
• Descriptor: Chaperone protein ClpB,ATP-dependent Clp protease ATP-binding subunit ClpA,Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (2 entities in total)
• Functional Keywords: chaperone, disaggregase, clpb, aaa
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 6
• Total formula weight: 589489.20

Authors

Deville, C.,Carroni, M.,Franke, K.B.,Topf, M.,Bukau, B.,Mogk, A.,Saibil, H.R. (deposition date: 2017-07-11, release date: 2017-08-16, Last modification date: 2019-11-06)

• Primary citation: Deville, C.,Carroni, M.,Franke, K.B.,Topf, M.,Bukau, B.,Mogk, A.,Saibil, H.R.; Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.; Sci Adv, 3:e1701726-e1701726, 2017; PubMed: 28798962; DOI: 10.1126/sciadv.1701726

Experimental method

ELECTRON MICROSCOPY (4.6 Å)