7PGR
The structure of human neurofibromin isoform 2 in closed conformation
Summary for 7PGR
Entry DOI | 10.2210/pdb7pgr/pdb |
EMDB information | 13393 |
Descriptor | Neurofibromin, ZINC ION (2 entities in total) |
Functional Keywords | neurofibromin, cancer, gap, ras, neurofibromatosis type 1, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 639646.13 |
Authors | Naschberger, A.,Baradaran, R.,Carroni, M.,Rupp, B. (deposition date: 2021-08-15, release date: 2021-11-17, Last modification date: 2021-11-24) |
Primary citation | Naschberger, A.,Baradaran, R.,Rupp, B.,Carroni, M. The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599:315-319, 2021 Cited by PubMed: 34707296DOI: 10.1038/s41586-021-04024-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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