7PGS

Consensus structure of human Neurofibromin isoform 2

Summary for 7PGS

Entry DOI	10.2210/pdb7pgs/pdb
EMDB information	13394
Descriptor	Neurofibromin, ZINC ION (2 entities in total)
Functional Keywords	neurofibromin, cancer, gap, ras, neurofibromatosis type 1, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	639580.72
Authors	Naschberger, A.,Baradaran, R.,Carroni, M.,Rupp, B. (deposition date: 2021-08-15, release date: 2021-11-17, Last modification date: 2021-11-24)
Primary citation	Naschberger, A.,Baradaran, R.,Rupp, B.,Carroni, M. The structure of neurofibromin isoform 2 reveals different functional states. Nature, 599:315-319, 2021 Cited by PubMed: 34707296 DOI: 10.1038/s41586-021-04024-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation