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3E2E
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BU of 3e2e by Molmil
Crystal Structure of an Intermediate Complex of T7 RNAP and 7nt of RNA
分子名称: DNA (28-MER), DNA (31-MER), DNA-directed RNA polymerase, ...
著者Durniak, K.J, Bailey, S, Steitz, T.A.
登録日2008-08-05
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of a transcribing t7 RNA polymerase in transition from initiation to elongation
Science, 322, 2008
3EDU
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BU of 3edu by Molmil
Crystal structure of the ankyrin-binding domain of human erythroid spectrin
分子名称: Spectrin beta chain, erythrocyte
著者Simonovic, M, Stabach, P, Simonovic, I, Steitz, T.A, Morrow, J.S.
登録日2008-09-03
公開日2009-02-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of the ankyrin-binding site of {beta}-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties
Blood, 113, 2009
4V8I
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BU of 4v8i by Molmil
Crystal structure of YfiA bound to the 70S ribosome.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Blaha, G.M, Steitz, T.A.
登録日2011-12-12
公開日2014-07-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Science, 336, 2012
4V9R
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BU of 4v9r by Molmil
Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A.
登録日2013-12-05
公開日2014-07-09
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
4V7Y
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BU of 4v7y by Molmil
Structure of the Thermus thermophilus 70S ribosome complexed with azithromycin.
分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A.
登録日2010-08-18
公開日2014-07-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V8H
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BU of 4v8h by Molmil
Crystal structure of HPF bound to the 70S ribosome.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Blaha, G.M, Steitz, T.A.
登録日2011-12-11
公開日2014-07-09
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis.
Science, 336, 2012
4V7X
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BU of 4v7x by Molmil
Structure of the Thermus thermophilus ribosome complexed with erythromycin.
分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A.
登録日2010-08-17
公開日2014-07-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V9S
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BU of 4v9s by Molmil
Crystal structure of antibiotic GE82832 bound to 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A.
登録日2013-12-05
公開日2014-07-09
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
4V95
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BU of 4v95 by Molmil
Crystal structure of YAEJ bound to the 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Gagnon, M.G, Seetharaman, S.V, Bulkley, D.P, Steitz, T.A.
登録日2012-01-27
公開日2014-07-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome.
Science, 335, 2012
4V8A
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BU of 4v8a by Molmil
The structure of thermorubin in complex with the 70S ribosome from Thermus thermophilus.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Bulkley, D, Johnson, F.A, Steitz, T.A.
登録日2011-12-05
公開日2014-07-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge b2a of the ribosome.
J.Mol.Biol., 416, 2012
1QSL
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BU of 1qsl by Molmil
KLENOW FRAGMENT COMPLEXED WITH SINGLE-STRANDED SUBSTRATE AND EUROPIUM (III) ION
分子名称: 5'-D(*GP*CP*TP*TP*AP*CP*GP*C)-3', DNA POLYMERASE I, EUROPIUM ION
著者Brautigam, C.A, Aschheim, K, Steitz, T.A.
登録日1999-06-22
公開日1999-06-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural elucidation of the binding and inhibitory properties of lanthanide (III) ions at the 3'-5' exonucleolytic active site of the Klenow fragment
Chem.Biol., 6, 1999
1REA
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BU of 1rea by Molmil
STRUCTURE OF THE RECA PROTEIN-ADP COMPLEX
分子名称: ADENOSINE-5'-DIPHOSPHATE, REC A
著者Story, R.M, Steitz, T.A.
登録日1991-12-19
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the recA protein-ADP complex.
Nature, 355, 1992
5DOX
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BU of 5dox by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with Hygromycin-A at 3.1A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
登録日2015-09-11
公開日2015-12-30
最終更新日2025-03-19
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
5DOY
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BU of 5doy by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic Hygromycin A, mRNA and three tRNAs in the A, P and E sites at 2.6A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
登録日2015-09-11
公開日2015-12-30
最終更新日2025-03-19
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
1TV6
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BU of 1tv6 by Molmil
HIV-1 Reverse Transcriptase Complexed with CP-94,707
分子名称: 3-[4-(2-METHYL-IMIDAZO[4,5-C]PYRIDIN-1-YL)BENZYL]-3H-BENZOTHIAZOL-2-ONE, reverse transcriptase p51 subunit, reverse transcriptase p66 subunit
著者Pata, J.D, Stirtan, W.G, Goldstein, S.W, Steitz, T.A.
登録日2004-06-28
公開日2004-07-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant RTs resistant to other non-nucleoside inhibitors
Proc.Natl.Acad.Sci.USA, 101, 2004
6MS4
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BU of 6ms4 by Molmil
Crystal structure of the DENR-MCT-1 complex
分子名称: Density-regulated protein, GLYCEROL, Malignant T-cell-amplified sequence 1, ...
著者Lomakin, I.B, Steitz, T.A, Dmitriev, S.E.
登録日2018-10-16
公開日2019-01-02
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
1VQ7
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BU of 1vq7 by Molmil
The structure of the transition state analogue "DCA" bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(5AA)P*(2OP)P*(PAE)P*AP*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.
Nature, 438, 2005
1VQN
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BU of 1vqn by Molmil
The structure of CC-HPMN AND CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(LOF))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.
Nature, 438, 2005
1VQ6
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BU of 1vq6 by Molmil
The structure of c-hpmn and CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*(5AA)*(HFA))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.
Nature, 438, 2005
1XI1
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BU of 1xi1 by Molmil
Phi29 DNA polymerase ssDNA complex, monoclinic crystal form
分子名称: 5'-D(P*TP*TP*TP*TP*T)-3', DNA polymerase, MAGNESIUM ION
著者Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2004-09-21
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Correction of X-ray intensities from single crystals containing lattice-translocation defects
Acta Crystallogr.,Sect.D, 61, 2005
1XHX
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BU of 1xhx by Molmil
Phi29 DNA Polymerase, orthorhombic crystal form
分子名称: DNA polymerase, MAGNESIUM ION, SULFATE ION
著者Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2004-09-21
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29
Mol.Cell, 16, 2004
1XHZ
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BU of 1xhz by Molmil
Phi29 DNA polymerase, orthorhombic crystal form, ssDNA complex
分子名称: 5'-D(*TP*TP*TP*TP*T)-3', DNA polymerase
著者Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
登録日2004-09-21
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29
Mol.Cell, 16, 2004
1B8H
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BU of 1b8h by Molmil
SLIDING CLAMP, DNA POLYMERASE
分子名称: DNA POLYMERASE PROCESSIVITY COMPONENT, DNA POLYMERASE fragment
著者Shamoo, Y, Steitz, T.A.
登録日1999-02-01
公開日1999-02-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex.
Cell(Cambridge,Mass.), 99, 1999
1BDN
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BU of 1bdn by Molmil
CRYSTAL LATTICE PACKING IS IMPORTANT IN DETERMINING THE BEND OF A DNA DODECAMER CONTAINING AN ADENINE TRACT
分子名称: DNA (5'-D(*CP*GP*CP*AP*AP*AP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*TP*TP*TP*TP*GP*CP*G)-3'), MAGNESIUM ION
著者DiGabriele, A.D, Sanderson, M.R, Steitz, T.A.
登録日1989-07-25
公開日1991-04-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal lattice packing is important in determining the bend of a DNA dodecamer containing an adenine tract.
Proc.Natl.Acad.Sci.USA, 86, 1989
1B77
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BU of 1b77 by Molmil
BUILDING A REPLISOME STRUCTURE FROM INTERACTING PIECES: A SLIDING CLAMP COMPLEXED WITH AN INTERACTION PEPTIDE FROM DNA POLYMERASE
分子名称: PROTEIN (SLIDING CLAMP)
著者Shamoo, Y, Steitz, T.A.
登録日1999-01-27
公開日1999-02-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex.
Cell(Cambridge,Mass.), 99, 1999

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