3EDU

Crystal structure of the ankyrin-binding domain of human erythroid spectrin

Summary for 3EDU

Entry DOI	10.2210/pdb3edu/pdb
Descriptor	Spectrin beta chain, erythrocyte (2 entities in total)
Functional Keywords	spectrin, ankyrin, ankyrin-binding domain, actin capping, actin-binding, cytoskeleton, disease mutation, elliptocytosis, hereditary hemolytic anemia, phosphoprotein, structural protein
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm, cytoskeleton: P11277
Total number of polymer chains	1
Total formula weight	24810.54
Authors	Simonovic, M.,Stabach, P.,Simonovic, I.,Steitz, T.A.,Morrow, J.S. (deposition date: 2008-09-03, release date: 2009-02-10, Last modification date: 2024-02-21)
Primary citation	Stabach, P.R.,Simonovic, I.,Ranieri, M.A.,Aboodi, M.S.,Steitz, T.A.,Simonovic, M.,Morrow, J.S. The structure of the ankyrin-binding site of {beta}-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties Blood, 113:5377-5384, 2009 Cited by PubMed: 19168783 DOI: 10.1182/blood-2008-10-184291 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation