Crystal structure of YfiA bound to the 70S ribosome.

This is a large structure.

Summary for 4V8I

Integrates3V2C 3V2D 3V2E 3V2F
Descriptor16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ... (56 entities in total)
Functional Keywordsribosome associated inhibitor a, raia, protein y, stress response, stationary phase, ribosome hibernation, ribosome-inhibitor complex, ribosome/inhibitor
Biological sourceEscherichia coli K-12
Total number of polymer chains106
Total molecular weight4412529.44
Polikanov, Y.S.,Blaha, G.M.,Steitz, T.A. (deposition date: 2011-12-12, release date: 2014-07-09, Last modification date: 2014-12-10)
Primary citation
Polikanov, Y.S.,Blaha, G.M.,Steitz, T.A.
How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Science, 336:915-918, 2012
PubMed: 22605777 (PDB entries with the same primary citation)
DOI: 10.1126/science.1218538
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.250121.1%15.3%7.5%0.49MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4v8i
no rotation
Molmil generated image of 4v8i
rotated about x axis by 90°
Molmil generated image of 4v8i
rotated about y axis by 90°
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