4V8A

The structure of thermorubin in complex with the 70S ribosome from Thermus thermophilus.

This is a non-PDB format compatible entry.

Summary for 4V8A

• Entry DOI: 10.2210/pdb4v8a/pdb
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (53 entities in total)
• Functional Keywords: ribosome, protein synthesis, thermorubin, ribosome-antibiotic complex, ribosome/antibiotic
• Biological source: Thermus thermophilus; More
• Total number of polymer chains: 102
• Total formula weight: 4328287.91

Authors

Bulkley, D.,Johnson, F.A.,Steitz, T.A. (deposition date: 2011-12-05, release date: 2014-07-09, Last modification date: 2014-12-10)

• Primary citation: Bulkley, D.,Johnson, F.,Steitz, T.A.; The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge b2a of the ribosome.; J.Mol.Biol., 416:571-578, 2012; PubMed: 22240456; DOI: 10.1016/j.jmb.2011.12.055

Experimental method

X-RAY DIFFRACTION (3.2 Å)