4V8A

The structure of thermorubin in complex with the 70S ribosome from Thermus thermophilus.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, EA (AA, BA)	23S ribosomal RNA	polymer	2915	947934.4	2	GenBank (AP008226.1)	Thermus thermophilus
2	B, FA (AB, BB)	5S ribosomal RNA	polymer	122	39510.5	2	GenBank (AP008226.1)	Thermus thermophilus
3	C, GA (AD, BD)	50S ribosomal protein L2	polymer	276	30532.6	2	UniProt (P60405) Pfam (PF00181) Pfam (PF03947)	Thermus thermophilus
4	D, HA (AE, BE)	50S ribosomal protein L3	polymer	206	22450.2	2	UniProt (Q5SHN8) Pfam (PF00297)	Thermus thermophilus
5	E, IA (AF, BF)	50S ribosomal protein L4	polymer	205	22712.2	2	UniProt (Q5SHN9) Pfam (PF00573)	Thermus thermophilus
6	F, JA (AG, BG)	50S ribosomal protein L5	polymer	182	21061.6	2	UniProt (Q5SHQ0) Pfam (PF00281) Pfam (PF00673)	Thermus thermophilus
7	G, KA (AH, BH)	50S ribosomal protein L6	polymer	180	19568.9	2	UniProt (Q5SHQ3)	Thermus thermophilus
8	H, LA (AI, BI)	50S ribosomal protein L9	polymer	148	16436.2	2	UniProt (Q5SLQ1) Pfam (PF01281) Pfam (PF03948)	Thermus thermophilus
9	I, MA (AN, BN)	50S ribosomal protein L13	polymer	140	15927.9	2	UniProt (P60488) Pfam (PF00572)	Thermus thermophilus
10	J, NA (AO, BO)	50S ribosomal protein L14	polymer	122	13323.6	2	UniProt (Q5SHP8) Pfam (PF00238)	Thermus thermophilus
11	K, OA (AP, BP)	50S ribosomal protein L15	polymer	150	16319.1	2	UniProt (Q5SHQ7) Pfam (PF00828)	Thermus thermophilus
12	L, PA (AQ, BQ)	50S ribosomal protein L16	polymer	141	15993.9	2	UniProt (P60489) Pfam (PF00252)	Thermus thermophilus
13	M, QA (AR, BR)	50S ribosomal protein L17	polymer	118	13750.1	2	UniProt (Q9Z9H5) Pfam (PF01196)	Thermus thermophilus
14	N, RA (AS, BS)	50S ribosomal protein L18	polymer	112	12639.8	2	UniProt (Q5SHQ4) Pfam (PF00861)	Thermus thermophilus
15	O, SA (AT, BT)	50S ribosomal protein L19	polymer	146	17188.8	2	UniProt (P60490) Pfam (PF01245)	Thermus thermophilus
16	P, TA (AU, BU)	50S ribosomal protein L20	polymer	118	13779.3	2	UniProt (P60491) Pfam (PF00453)	Thermus thermophilus
17	Q, UA (AV, BV)	50S ribosomal protein L21	polymer	101	11069.2	2	UniProt (P60492) Pfam (PF00829)	Thermus thermophilus
18	R, VA (AW, BW)	50S ribosomal protein L22	polymer	113	12808.1	2	UniProt (Q5SHP3) Pfam (PF00237)	Thermus thermophilus
19	S, WA (AX, BX)	50S ribosomal protein L23	polymer	96	10759.8	2	UniProt (Q5SHP0) Pfam (PF00276)	Thermus thermophilus
20	T, XA (AY, BY)	50S ribosomal protein L24	polymer	110	12085.6	2	UniProt (Q5SHP9) Pfam (PF00467) Pfam (PF17136)	Thermus thermophilus
21	U, YA (AZ, BZ)	50S ribosomal protein L25	polymer	206	23238.6	2	UniProt (Q5SHZ1) Pfam (PF01386) Pfam (PF14693)	Thermus thermophilus
22	V, ZA (A0, B0)	50S ribosomal protein L27	polymer	85	9529.1	2	UniProt (P60493) Pfam (PF01016)	Thermus thermophilus
23	AB, W (A1, B1)	50S ribosomal protein L28	polymer	98	11004.2	2	UniProt (P60494) Pfam (PF00830)	Thermus thermophilus
24	BB, X (A2, B2)	50S ribosomal protein L29	polymer	72	8670.3	2	UniProt (Q5SHP6) Pfam (PF00831)	Thermus thermophilus
25	CB, Y (A3, B3)	50S ribosomal protein L30	polymer	60	6799.1	2	UniProt (Q5SHQ6) Pfam (PF00327)	Thermus thermophilus
26	DB, Z (A4, B4)	50S ribosomal protein L31	polymer	71	8300.5	2	UniProt (Q5SJE1) Pfam (PF01197)	Thermus thermophilus
27	AA, EB (A5, B5)	50S ribosomal protein L32	polymer	60	6722.1	2	UniProt (P80339) Pfam (PF01783)	Thermus thermophilus
28	BA, FB (A6, B6)	50S ribosomal protein L33	polymer	54	6632.9	2	UniProt (P35871) Pfam (PF00471)	Thermus thermophilus
29	CA, GB (A7, B7)	50S ribosomal protein L34	polymer	49	6132.4	2	UniProt (P80340) Pfam (PF00468)	Thermus thermophilus
30	DA, HB (A8, B8)	50S ribosomal protein L35	polymer	65	7506.2	2	UniProt (Q5SKU1) Pfam (PF01632)	Thermus thermophilus
31	DC, IB (CA, DA)	16S ribosomal RNA	polymer	1521	493652.2	2	GenBank (AP008226.1)	Thermus thermophilus
32	EC, JB (CB, DB)	30S ribosomal protein S2	polymer	256	29317.7	2	UniProt (P80371) Pfam (PF00318)	Thermus thermophilus
33	FC, KB (CC, DC)	30S ribosomal protein S3	polymer	239	26751.1	2	UniProt (P80372) Pfam (PF07650) Pfam (PF00189)	Thermus thermophilus
34	GC, LB (CD, DD)	30S ribosomal protein S4	polymer	209	24373.4	2	UniProt (P80373) Pfam (PF00163) Pfam (PF01479)	Thermus thermophilus
35	HC, MB (CE, DE)	30S ribosomal protein S5	polymer	162	17583.4	2	UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719)	Thermus thermophilus
36	IC, NB (CF, DF)	30S ribosomal protein S6	polymer	101	11988.8	2	UniProt (Q5SLP8) Pfam (PF01250)	Thermus thermophilus
37	JC, OB (CG, DG)	30S ribosomal protein S7	polymer	156	18051.0	2	UniProt (P17291) Pfam (PF00177)	Thermus thermophilus
38	KC, PB (CH, DH)	30S ribosomal protein S8	polymer	138	15868.6	2	UniProt (Q5SHQ2)	Thermus thermophilus
39	LC, QB (CI, DI)	30S ribosomal protein S9	polymer	128	14429.7	2	UniProt (P80374) Pfam (PF00380)	Thermus thermophilus
40	MC, RB (CJ, DJ)	30S ribosomal protein S10	polymer	105	11955.0	2	UniProt (Q5SHN7) Pfam (PF00338)	Thermus thermophilus
41	NC, SB (CK, DK)	30S ribosomal protein S11	polymer	129	13737.9	2	UniProt (P80376) Pfam (PF00411)	Thermus thermophilus
42	OC, TB (CL, DL)	30S ribosomal protein S12	polymer	132	14637.4	2	UniProt (Q5SHN3) Pfam (PF00164)	Thermus thermophilus
43	PC, UB (CM, DM)	30S ribosomal protein S13	polymer	126	14338.9	2	UniProt (P80377) Pfam (PF00416)	Thermus thermophilus
44	QC, VB (CN, DN)	30S ribosomal protein S14	polymer	61	7158.7	2	UniProt (Q5SHQ1)	Thermus thermophilus
45	RC, WB (CO, DO)	30S ribosomal protein S15	polymer	89	10578.4	2	UniProt (Q5SJ76) Pfam (PF00312)	Thermus thermophilus
46	SC, XB (CP, DP)	30S ribosomal protein S16	polymer	88	10410.0	2	UniProt (Q5SJH3) Pfam (PF00886)	Thermus thermophilus
47	TC, YB (CQ, DQ)	30S ribosomal protein S17	polymer	105	12325.7	2	UniProt (Q5SHP7)	Thermus thermophilus
48	UC, ZB (CR, DR)	30S ribosomal protein S18	polymer	88	10258.3	2	UniProt (Q5SLQ0) Pfam (PF01084)	Thermus thermophilus
49	AC, VC (CS, DS)	30S ribosomal protein S19	polymer	93	10605.5	2	UniProt (Q5SHP2) Pfam (PF00203)	Thermus thermophilus
50	BC, WC (CT, DT)	30S ribosomal protein S20	polymer	106	11736.1	2	UniProt (P80380) Pfam (PF01649)	Thermus thermophilus
51	CC, XC (CU, DU)	30S ribosomal protein THX	polymer	27	3350.0	2	UniProt (Q5SIH3) Pfam (PF17070)	Thermus thermophilus
52	BD, YC (BA, AA)	Thermorubin	non-polymer		600.5	2	Chemie (T8B)
53	AD, CD, DD, ZC (AA, BA)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)

Sequence modifications

AA, BA: 2 - 2907 (GenBank: AP008226.1)

PDB	External Database	Details
G 272	U 352315	conflict

AB, BB: 1 - 122 (GenBank: AP008226.1)

PDB	External Database	Details
G 120	A 12354	conflict

AI, BI: 1 - 148 (UniProt: Q5SLQ1)

PDB	External Database	Details
Glu 110	Asp 110	conflict

CA, DA: 0 - 1544 (GenBank: AP008226.1)

PDB	External Database	Details
-	U 131385	deletion

CI, DI: 1 - 128 (UniProt: P80374)

PDB	External Database	Details
Arg 58	His 58	conflict

CJ, DJ: 1 - 105 (UniProt: Q5SHN7)

PDB	External Database	Details
Leu 75	Ile 75	conflict

Contents of the asymmetric unit

Polymers	Number of chains	102
	Total formula weight	4326989.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1298.3
All*	Total formula weight	4328287.9

*Water molecules are not included.