7AYR
 
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7AYQ
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6TRW
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5AZU
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6QZW
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7A3F
 | | Crystal structure of apo DPP9 | | 分子名称: | Dipeptidyl peptidase 9, GLYCEROL, PHOSPHATE ION | | 著者 | Ross, B.H, Huber, R. | | 登録日 | 2020-08-18 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Discovery and Development of 4-Oxo-beta-Lactams as Novel Inhibitors of Dipeptidyl Peptidases 8 and 9
To Be Published
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7A3I
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7A3K
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5JDW
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6T41
 | | CDK8/Cyclin C in complex with N-(4-chlorobenzyl)isoquinolin-4-amine | | 分子名称: | 1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ... | | 著者 | Schneider, E.V, Maskos, K, Huber, R, Kuhn, C.-D. | | 登録日 | 2019-10-11 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A precisely positioned MED12 activation helix stimulates CDK8 kinase activity.
Proc.Natl.Acad.Sci.USA, 117, 2020
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1N2T
 | | C-DES Mutant K223A with GLY Covalenty Linked to the PLP-cofactor | | 分子名称: | GLYCINE, L-cysteine/cystine lyase C-DES, POTASSIUM ION, ... | | 著者 | Kaiser, J.T, Bruno, S, Clausen, T, Huber, R, Schiaretti, F, Mozzarelli, A, Kessler, D. | | 登録日 | 2002-10-24 | | 公開日 | 2003-01-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Snapshots of the Cystine Lyase "C-DES" during Catalysis: Studies in Solution and in the Crystalline State
J.Biol.Chem., 278, 2003
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1N3R
 | | Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | | 分子名称: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | | 著者 | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-10-29 | | 公開日 | 2003-10-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I
J.MOL.BIOL., 326, 2003
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1N06
 | | Crystal Structure of Schizosaccharomyces pombe Riboflavin Kinase Reveals a Novel ATP and Riboflavin Binding Fold | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, PUTATIVE riboflavin kinase | | 著者 | Bauer, S, Kemter, K, Bacher, A, Huber, R, Fischer, M, Steinbacher, S. | | 登録日 | 2002-10-11 | | 公開日 | 2003-02-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Schizosaccharomyces pombe Riboflavin Kinase Reveals a Novel ATP and Riboflavin Binding Fold
J.Mol.Biol., 326, 2003
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7OR4
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7NVQ
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5JXH
 | | Structure the proprotein convertase furin in complex with meta-guanidinomethyl-Phac-RVR-Amba at 2.0 Angstrom resolution. | | 分子名称: | 2UC-ARG-VAL-ARG-00S, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E. | | 登録日 | 2016-05-13 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5JXJ
 | | Structure of the proprotein convertase furin complexed to meta-guanidinomethyl-Phac-RVR-Amba in presence of EDTA | | 分子名称: | 2UC-ARG-VAL-ARG-00S, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E. | | 登録日 | 2016-05-13 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6EOP
 | | DPP8 - SLRFLYEG, space group 20 | | 分子名称: | CALCIUM ION, CITRATE ANION, Dipeptidyl peptidase 8, ... | | 著者 | Ross, B.R, Huber, R. | | 登録日 | 2017-10-10 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6EOT
 | | DPP8 - SLRFLYEG, space group 19 | | 分子名称: | Dipeptidyl peptidase 8, SER-LEU-ARG-PHE-LEU-TYR-GLU-GLY | | 著者 | Ross, B.R, Huber, R. | | 登録日 | 2017-10-10 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6EOO
 | | DPP8 - Apo, space group 20 | | 分子名称: | Dipeptidyl peptidase 8 | | 著者 | Ross, B.R, Huber, R. | | 登録日 | 2017-10-10 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6EOS
 | | DPP8 - Apo, space group 19 | | 分子名称: | Dipeptidyl peptidase 8 | | 著者 | Ross, B.R, Huber, R. | | 登録日 | 2017-10-10 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6EOR
 | | DPP9 - 1G244 | | 分子名称: | (2~{S})-2-azanyl-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione, Dipeptidyl peptidase 9 | | 著者 | Ross, B.R, Huber, R. | | 登録日 | 2017-10-10 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6EOQ
 | | DPP9 - Apo | | 分子名称: | Dipeptidyl peptidase 9 | | 著者 | Ross, B.R, Huber, R. | | 登録日 | 2017-10-10 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6JDW
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1A24
 | | SOLUTION NMR STRUCTURE OF REDUCED DSBA FROM ESCHERICHIA COLI, FAMILY OF 20 STRUCTURES | | 分子名称: | DSBA | | 著者 | Schirra, H.J, Renner, C, Czisch, M, Huber-Wunderlich, M, Holak, T.A, Glockshuber, R. | | 登録日 | 1998-01-15 | | 公開日 | 1998-09-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of reduced DsbA from Escherichia coli in solution.
Biochemistry, 37, 1998
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