6JDW

CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH GAMMA-AMINO BUTYRIC ACID

Summary for 6JDW

Entry DOI	10.2210/pdb6jdw/pdb
Descriptor	PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE), GAMMA-AMINO-BUTANOIC ACID (3 entities in total)
Functional Keywords	transferase, creatine biosynthesis, catalytic triad, reaction mechanism, novel fold, fivefold pseudosymmetry
Biological source	Homo sapiens (human)
Cellular location	Isoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Isoform 2: Cytoplasm: P50440
Total number of polymer chains	1
Total formula weight	44444.61
Authors	Fritsche, E.,Humm, A.,Huber, R. (deposition date: 1998-10-12, release date: 1999-02-09, Last modification date: 2023-11-15)
Primary citation	Fritsche, E.,Humm, A.,Huber, R. The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study. J.Biol.Chem., 274:3026-3032, 1999 Cited by PubMed: 9915841 DOI: 10.1074/jbc.274.5.3026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation