6NKO
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![BU of 6nko by Molmil](/molmil-images/mine/6nko) | Crystal structure of ForH | 分子名称: | ForH | 著者 | Zheng, J, Irani, S, Zhang, Y. | 登録日 | 2019-01-07 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | 主引用文献 | Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis. J. Am. Chem. Soc., 141, 2019
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6NBF
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![BU of 6nbf by Molmil](/molmil-images/mine/6nbf) | Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | 分子名称: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | 登録日 | 2018-12-07 | 公開日 | 2019-04-17 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
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7V1U
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![BU of 7v1u by Molmil](/molmil-images/mine/7v1u) | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor ZJ12 | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(3-ethyl-6-methoxy-1,2-benzoxazol-5-yl)-2-methoxy-benzenesulfonamide | 著者 | Zhang, M, Wang, C, Zhang, C, Zhang, Y, Xu, Y. | 登録日 | 2021-08-06 | 公開日 | 2022-08-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia. Acta Pharmacol.Sin., 43, 2022
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7V2J
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![BU of 7v2j by Molmil](/molmil-images/mine/7v2j) | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 33 | 分子名称: | Bromodomain-containing protein 4, ~{N}-(3-ethyl-6-methoxy-1,2-benzoxazol-5-yl)-4-methoxy-benzenesulfonamide | 著者 | Zhang, M, Wang, C, Zhang, C, Zhang, Y, Xu, Y. | 登録日 | 2021-08-09 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia. Acta Pharmacol.Sin., 43, 2022
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6NBI
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![BU of 6nbi by Molmil](/molmil-images/mine/6nbi) | Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | 分子名称: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | 登録日 | 2018-12-07 | 公開日 | 2019-04-17 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
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2FF0
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![BU of 2ff0 by Molmil](/molmil-images/mine/2ff0) | Solution Structure of Steroidogenic Factor 1 DNA Binding Domain Bound to its Target Sequence in the Inhibin alpha-subunit Promoter | 分子名称: | CTGTGGCCCTGAGCC, GGCTCAGGGCCACAG, Steroidogenic factor 1, ... | 著者 | Little, T.H, Zhang, Y, Matulis, C.K, Weck, J, Zhang, Z, Ramachandran, A, Mayo, K.E, Radhakrishnan, I. | 登録日 | 2005-12-17 | 公開日 | 2006-04-11 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Sequence-specific deoxyribonucleic Acid (DNA) recognition by steroidogenic factor 1: a helix at the carboxy terminus of the DNA binding domain is necessary for complex stability. Mol.Endocrinol., 20, 2006
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6LK8
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![BU of 6lk8 by Molmil](/molmil-images/mine/6lk8) | Structure of Xenopus laevis Cytoplasmic Ring subunit. | 分子名称: | GATOR complex protein SEC13, MGC154553 protein, MGC83295 protein, ... | 著者 | Shi, Y, Huang, G, Yan, C, Zhang, Y. | 登録日 | 2019-12-18 | 公開日 | 2021-07-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis. Cell Res., 30, 2020
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1P9Z
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![BU of 1p9z by Molmil](/molmil-images/mine/1p9z) | The Solution Structure of Antifungal Peptide Distinct With a Five-disulfide Motif from Eucommia ulmoides Oliver | 分子名称: | Eucommia Antifungal peptide 2 | 著者 | Huang, R.H, Xiang, Y, Tu, G.Z, Zhang, Y, Wang, D.C. | 登録日 | 2003-05-13 | 公開日 | 2004-05-25 | 最終更新日 | 2019-12-25 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of Eucommia Antifungal Peptide: A Novel Structural Model Distinct with a Five-Disulfide Motif. Biochemistry, 43, 2004
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8T2I
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![BU of 8t2i by Molmil](/molmil-images/mine/8t2i) | Negative stain EM assembly of MYC, JAZ, and NINJA complex | 分子名称: | AFP homolog 2, Maltose/maltodextrin-binding periplasmic protein, Protein TIFY 10A, ... | 著者 | Zhou, X.E, Zhang, Y, Zhou, Y, He, Q, Cao, X, Kariapper, L, Suino-Powell, K, Zhu, Y, Zhang, F, Karsten, M. | 登録日 | 2023-06-06 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (10.4 Å) | 主引用文献 | Assembly of JAZ-JAZ and JAZ-NINJA complexes in jasmonate signaling. Plant Commun., 4, 2023
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3JCS
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![BU of 3jcs by Molmil](/molmil-images/mine/3jcs) | 2.8 Angstrom cryo-EM structure of the large ribosomal subunit from the eukaryotic parasite Leishmania | 分子名称: | 26S alpha ribosomal RNA, 26S delta ribosomal RNA, 26S epsilon ribosomal RNA, ... | 著者 | Shalev-Benami, M, Zhang, Y, Matzov, D, Halfon, Y, Zackay, A, Rozenberg, H, Zimmerman, E, Bashan, A, Jaffe, C.L, Yonath, A, Skiniotis, G. | 登録日 | 2016-01-21 | 公開日 | 2016-07-20 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | 2.8- angstrom Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania. Cell Rep, 16, 2016
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6ND7
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![BU of 6nd7 by Molmil](/molmil-images/mine/6nd7) | The crystal structure of TerB co-crystallized with polyporic acid | 分子名称: | 2~3~,2~6~-dihydroxy[1~1~,2~1~:2~4~,3~1~-terphenyl]-2~2~,2~5~-dione, GLYCEROL, ISOPROPYL ALCOHOL, ... | 著者 | Clinger, J.A, Elshahawi, S.I, Zhang, Y, Hall, R.P, Liu, Y, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2018-12-13 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC To Be Published
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8HDZ
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![BU of 8hdz by Molmil](/molmil-images/mine/8hdz) | Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in an apo form | 分子名称: | A22 DNA replication processivity factor, E4 uracil-DNA glycosylase, F8 DNA polymerase | 著者 | Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C. | 登録日 | 2022-11-07 | 公開日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex. Cell Res., 33, 2023
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5B7J
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![BU of 5b7j by Molmil](/molmil-images/mine/5b7j) | Structure model of Sap1-DNA complex | 分子名称: | DNA (5'-D(*AP*AP*TP*AP*TP*TP*GP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*AP*TP*AP*TP*T)-3'), Switch-activating protein 1 | 著者 | Jin, C, Hu, Y, Ding, J, Zhang, Y. | 登録日 | 2016-06-07 | 公開日 | 2017-02-22 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe J. Biol. Chem., 292, 2017
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5F67
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![BU of 5f67 by Molmil](/molmil-images/mine/5f67) | An exquisitely specific PDZ/target recognition revealed by the structure of INAD PDZ3 in complex with TRP channel tail | 分子名称: | Inactivation-no-after-potential D protein, TRP C terminal Tail | 著者 | Ye, F, Shang, Y, Liu, W, Zhang, M. | 登録日 | 2015-12-05 | 公開日 | 2016-02-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | An Exquisitely Specific PDZ/Target Recognition Revealed by the Structure of INAD PDZ3 in Complex with TRP Channel Tail Structure, 24, 2016
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8GS8
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![BU of 8gs8 by Molmil](/molmil-images/mine/8gs8) | cryo-EM structure of the human respiratory complex II | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | 著者 | Du, Z, Zhou, X, Lai, Y, Xu, J, Zhang, Y, Zhou, S, Liu, F, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2022-09-05 | 公開日 | 2023-05-10 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structure of the human respiratory complex II. Proc.Natl.Acad.Sci.USA, 120, 2023
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5H3D
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![BU of 5h3d by Molmil](/molmil-images/mine/5h3d) | Helical structure of membrane tubules decorated by ACAP1 (BARPH doamin) protein by cryo-electron microscopy and MD simulation | 分子名称: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 | 著者 | Chan, C, Pang, X.Y, Zhang, Y, Sun, F, Fan, J. | 登録日 | 2016-10-22 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | ACAP1 assembles into an unusual protein lattice for membrane deformation through multiple stages. Plos Comput.Biol., 15, 2019
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4WVX
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![BU of 4wvx by Molmil](/molmil-images/mine/4wvx) | Crystal structure of a phosphotriesterase-like lactonase Gkap in native form | 分子名称: | 1,2-ETHANEDIOL, COBALT (II) ION, Phosphotriesterase | 著者 | An, J, Zhang, Y, Yang, G.Y, Feng, Y. | 登録日 | 2014-11-07 | 公開日 | 2015-11-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides To Be Published
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8H02
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8H9I
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![BU of 8h9i by Molmil](/molmil-images/mine/8h9i) | Human ATP synthase F1 domain, state2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | 著者 | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2022-10-25 | 公開日 | 2023-05-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9Q
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![BU of 8h9q by Molmil](/molmil-images/mine/8h9q) | Human ATP synthase state 3b subregion 3 | 分子名称: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | 著者 | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2022-10-25 | 公開日 | 2023-05-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9R
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![BU of 8h9r by Molmil](/molmil-images/mine/8h9r) | Human ATP synthase state 3b subregion 2 | 分子名称: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase subunit d, ... | 著者 | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2022-10-25 | 公開日 | 2023-05-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9P
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![BU of 8h9p by Molmil](/molmil-images/mine/8h9p) | Human ATP synthase F1 domain, state 3b | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit O, ... | 著者 | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2022-10-25 | 公開日 | 2023-05-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9U
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![BU of 8h9u by Molmil](/molmil-images/mine/8h9u) | Human ATP synthase state 3a (combined) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | 著者 | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2022-10-25 | 公開日 | 2023-05-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | 主引用文献 | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9V
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![BU of 8h9v by Molmil](/molmil-images/mine/8h9v) | Human ATP synthase state 3b (combined) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | 著者 | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2022-10-25 | 公開日 | 2023-05-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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8H9M
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![BU of 8h9m by Molmil](/molmil-images/mine/8h9m) | Human ATP synthase state 3a subregion 3 | 分子名称: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | 著者 | Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2022-10-25 | 公開日 | 2023-05-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the human ATP synthase. Mol.Cell, 83, 2023
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