7CYQ
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![BU of 7cyq by Molmil](/molmil-images/mine/7cyq) | Cryo-EM structure of an extended SARS-CoV-2 replication and transcription complex reveals an intermediate state in cap synthesis | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Helicase, MAGNESIUM ION, ... | 著者 | Yan, L, Ge, J, Zheng, L, Zhang, Y, Gao, Y, Wang, T, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | 登録日 | 2020-09-04 | 公開日 | 2020-12-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis. Cell, 184, 2021
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7DDN
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![BU of 7ddn by Molmil](/molmil-images/mine/7ddn) | SARS-Cov2 S protein at open state | 分子名称: | Spike glycoprotein | 著者 | Cong, Y, Liu, C.X. | 登録日 | 2020-10-29 | 公開日 | 2020-11-25 | 最終更新日 | 2021-01-27 | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | 主引用文献 | Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections. Nat Commun, 12, 2021
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3SE8
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![BU of 3se8 by Molmil](/molmil-images/mine/3se8) | Crystal structure of broadly and potently neutralizing antibody VRC03 in complex with HIV-1 gp120 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kwong, P.D, Zhou, T. | 登録日 | 2011-06-10 | 公開日 | 2011-08-10 | 最終更新日 | 2021-04-07 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science, 333, 2011
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7BZ5
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![BU of 7bz5 by Molmil](/molmil-images/mine/7bz5) | Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of B38, Light chain of B38, ... | 著者 | Wu, Y, Qi, J, Gao, F. | 登録日 | 2020-04-26 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2. Science, 368, 2020
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5ESZ
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![BU of 5esz by Molmil](/molmil-images/mine/5esz) | Crystal Structure of Broadly Neutralizing Antibody CH04, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade AE Strain A244 | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH04 Heavy Chain, ... | 著者 | Gorman, J, Yang, M, Kwong, P.D. | 登録日 | 2015-11-17 | 公開日 | 2015-12-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (4.191 Å) | 主引用文献 | Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nat. Struct. Mol. Biol., 23, 2016
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5ESV
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![BU of 5esv by Molmil](/molmil-images/mine/5esv) | Crystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade C Superinfecting Strain of Donor CAP256. | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gorman, J, Yang, M, Kwong, P.D. | 登録日 | 2015-11-17 | 公開日 | 2015-12-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.105 Å) | 主引用文献 | Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nat.Struct.Mol.Biol., 23, 2016
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7C2L
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![BU of 7c2l by Molmil](/molmil-images/mine/7c2l) | S protein of SARS-CoV-2 in complex bound with 4A8 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, R.H, Zhang, Y.Y, Guo, Y.Y, Li, Y.N, Xia, L, Zhou, Q. | 登録日 | 2020-05-08 | 公開日 | 2020-07-01 | 最終更新日 | 2021-02-17 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2. Science, 369, 2020
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6L3X
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![BU of 6l3x by Molmil](/molmil-images/mine/6l3x) | Discovery of novel peptidomimetic boronate ClpP inhibitors with noncanonical enzyme mechanism as potent virulence blockers in vitro and in vivo | 分子名称: | ATP-dependent Clp protease proteolytic subunit, [(1~{R})-1-[[(2~{S})-2-[[2,5-bis(chloranyl)phenyl]carbonylamino]-3-(1~{H}-indol-3-yl)propanoyl]amino]-3-methyl-butyl]boronic acid | 著者 | Luo, Y.F, Bao, R, Ju, Y, He, L.H. | 登録日 | 2019-10-15 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3054 Å) | 主引用文献 | Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockersin Vitroandin Vivo. J.Med.Chem., 63, 2020
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6O5B
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![BU of 6o5b by Molmil](/molmil-images/mine/6o5b) | Monomer of a cation channel | 分子名称: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | 著者 | Wang, Y, Bai, X, Jiang, Y. | 登録日 | 2019-03-01 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter. Cell, 177, 2019
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6LNL
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![BU of 6lnl by Molmil](/molmil-images/mine/6lnl) | ASFV core shell protein p15 | 分子名称: | 60 kDa polyprotein | 著者 | Guo, F, Shi, Y, Peng, G. | 登録日 | 2019-12-30 | 公開日 | 2020-12-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9286 Å) | 主引用文献 | The structural basis of African swine fever virus core shell protein p15 binding to DNA. Faseb J., 35, 2021
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8TS0
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![BU of 8ts0 by Molmil](/molmil-images/mine/8ts0) | |
5K6H
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![BU of 5k6h by Molmil](/molmil-images/mine/5k6h) | |
5K6I
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![BU of 5k6i by Molmil](/molmil-images/mine/5k6i) | Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 A149C-Y458C, S46G-E92D-S215P-K465Q variant. | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ... | 著者 | Joyce, M.G, Zhang, B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-08-17 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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7K58
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![BU of 7k58 by Molmil](/molmil-images/mine/7k58) | |
7K5B
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![BU of 7k5b by Molmil](/molmil-images/mine/7k5b) | |
7DK3
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![BU of 7dk3 by Molmil](/molmil-images/mine/7dk3) | SARS-CoV-2 S trimer, S-open | 分子名称: | Spike glycoprotein | 著者 | Xu, C, Cong, Y. | 登録日 | 2020-11-23 | 公開日 | 2020-12-16 | 最終更新日 | 2021-02-17 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM. Sci Adv, 7, 2021
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7KEK
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![BU of 7kek by Molmil](/molmil-images/mine/7kek) | |
4XMP
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![BU of 4xmp by Molmil](/molmil-images/mine/4xmp) | Crystal structure of broadly and potently neutralizing antibody VRC08 in complex with HIV-1 clade A strain Q842.d12 gp120 | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, ... | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | 登録日 | 2015-01-15 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.7831 Å) | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161, 2015
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5LVY
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![BU of 5lvy by Molmil](/molmil-images/mine/5lvy) | |
4XVS
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![BU of 4xvs by Molmil](/molmil-images/mine/4xvs) | Crystal structure of HIV-1 donor 45 d45-01dG5 coreE gp120 with antibody 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 Light chain, Donor 45 01dG5 coreE gp120, ... | 著者 | Joyce, M.G, Mascola, J.R, Kwong, P.D. | 登録日 | 2015-01-27 | 公開日 | 2015-05-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161, 2015
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4XNZ
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![BU of 4xnz by Molmil](/molmil-images/mine/4xnz) | Crystal structure of broadly and potently neutralizing antibody VRC06B in complex with HIV-1 clade A/E strain 93TH057 gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160, ... | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | 登録日 | 2015-01-16 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.389 Å) | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161, 2015
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4XNY
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![BU of 4xny by Molmil](/molmil-images/mine/4xny) | Crystal structure of broadly and potently neutralizing antibody VRC08C in complex with HIV-1 clade A strain Q842.d12 gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY VRC08C, ... | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | 登録日 | 2015-01-16 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161, 2015
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4XVT
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![BU of 4xvt by Molmil](/molmil-images/mine/4xvt) | Crystal structure of HIV-1 93TH057 coreE gp120 with antibody 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995) Light chain, ENVELOPE GLYCOPROTEIN GP120 OF HIV-1 CLADE A/E, ... | 著者 | Joyce, M.G, Mascola, J.R, Kwong, P.D. | 登録日 | 2015-01-28 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161, 2015
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5LQ7
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![BU of 5lq7 by Molmil](/molmil-images/mine/5lq7) | Salmonella effector SpvD - G161 variant | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Przydacz, M, Grabe, G.J, Holden, D.W, Hare, S.A. | 登録日 | 2016-08-16 | 公開日 | 2016-11-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence. J. Biol. Chem., 291, 2016
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7KC1
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![BU of 7kc1 by Molmil](/molmil-images/mine/7kc1) | |