8TS0

Crystal Structure of human ASGR1 CRD (Carbohydrate Recognition Domain) bound to 8M24 Fab

Summary for 8TS0

• Entry DOI: 10.2210/pdb8ts0/pdb
• Descriptor: 8M24 Fab Heavy chain, 8M24 Fab Light chain, Asialoglycoprotein receptor 1, ... (6 entities in total)
• Functional Keywords: asgr, asgpr, 8m24, endocytosis, sugar binding protein, sugar binding protein-immune system complex, sugar binding protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 69229.42

Authors

Sampathkumar, P.,Li, Y. (deposition date: 2023-08-10, release date: 2024-06-19)

• Primary citation: Sampathkumar, P.,Jung, H.,Chen, H.,Zhang, Z.,Suen, N.,Yang, Y.,Huang, Z.,Lopez, T.,Benisch, R.,Lee, S.J.,Ye, J.,Yeh, W.C.,Li, Y.; Targeted protein degradation systems to enhance Wnt signaling.; Elife, 13:-, 2024; PubMed: 38847394; DOI: 10.7554/eLife.93908

Experimental method

X-RAY DIFFRACTION (1.7 Å)