8TS0
Crystal Structure of human ASGR1 CRD (Carbohydrate Recognition Domain) bound to 8M24 Fab
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| H | TYR203-HIS209 | |
| L | TYR192-HIS198 |
| site_id | PS00615 |
| Number of Residues | 23 |
| Details | C_TYPE_LECTIN_1 C-type lectin domain signature. CAhftddgr.....WNDDVCqrpyr.WVC |
| Chain | Residue | Details |
| A | CYS255-CYS277 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 11 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | VAL191 | |
| A | ASP266 | |
| A | GLU278 | |
| A | GLU197 | |
| A | ASP216 | |
| A | GLN240 | |
| A | ASP242 | |
| A | ASP243 | |
| A | GLU253 | |
| A | ASP254 | |
| A | ASN265 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER285 |
