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8G83
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BU of 8g83 by Molmil
Structure of NAD+ consuming protein Acinetobacter baumannii TIR domain
分子名称: NAD(+) hydrolase AbTIR
著者Klontz, E.H, Wang, Y, Glendening, G, Carr, J, Tsibouris, T, Buddula, S, Nallar, S, Soares, A, Snyder, G.A.
登録日2023-02-17
公開日2023-10-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献The structure of NAD + consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.
J.Biol.Chem., 299, 2023
6JD7
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BU of 6jd7 by Molmil
Crystal structure of anti-CRISPR protein AcrIIC2 dimer
分子名称: ACETATE ION, AcrIIC2, MAGNESIUM ION
著者Cheng, Z, Huang, X, Sun, W, Wang, Y.L.
登録日2019-01-31
公開日2019-05-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
4I7F
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BU of 4i7f by Molmil
HIV-1 Reverse Transcriptase in complex with a phosphonate analog of nevirapine
分子名称: CHLORIDE ION, MAGNESIUM ION, Reverse transcriptase, ...
著者Lansdon, E.B, Parrish, J.
登録日2012-11-30
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Synthesis and biological evaluation of phosphonate analogues of nevirapine.
Bioorg.Med.Chem.Lett., 23, 2013
8WYP
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BU of 8wyp by Molmil
High Resolution Crystal Structure of Brd4 BD-1 in Complex with a Novel Inhibitor Precursor
分子名称: 3-bromanylimidazo[1,2-a]pyridin-6-amine, Bromodomain-containing protein 4
著者Liu, B, Ma, X.
登録日2023-10-31
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献High resolution crystal structure of BRD4-BD1 in complex with a novel inhibitor precursor.
Biochem.Biophys.Res.Commun., 690, 2024
6JDJ
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BU of 6jdj by Molmil
Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9
分子名称: AcrIIC2, CRISPR-associated endonuclease Cas9
著者Cheng, Z, Huang, X, Sun, W, Wang, Y.
登録日2019-02-01
公開日2019-05-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
6IZO
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BU of 6izo by Molmil
Crystal structure of DNA polymerase sliding clamp from Caulobacter crescentus
分子名称: 1,2-ETHANEDIOL, Beta sliding clamp, DI(HYDROXYETHYL)ETHER
著者Jiang, X, Zhang, L, Teng, M, Li, X.
登録日2018-12-20
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Caulobacter crescentus beta sliding clamp employs a noncanonical regulatory model of DNA replication.
Febs J., 287, 2020
6JDX
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BU of 6jdx by Molmil
Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 preprocessed with protease alpha-Chymotrypsin
分子名称: 1,2-ETHANEDIOL, AcrIIC2, CRISPR-associated endonuclease Cas9
著者Cheng, Z, Huang, X, Sun, W, Wang, Y.
登録日2019-02-02
公開日2019-05-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
4TZ4
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BU of 4tz4 by Molmil
Crystal Structure of Human Cereblon in Complex with DDB1 and Lenalidomide
分子名称: DNA damage-binding protein 1, Protein cereblon, S-Lenalidomide, ...
著者Chamberlain, P.P, Pagarigan, B, Delker, S, Leon, B, Riley, M.
登録日2014-07-09
公開日2014-08-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex
To Be Published
8TXT
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BU of 8txt by Molmil
Crystal structure of 05.GC.w13.02 Fab in complex with H5 HA from A/Viet Nam/1203/2004(H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_W13B_B, ...
著者Lin, T.H, Moore, N, Wilson, I.A.
登録日2023-08-24
公開日2024-06-26
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Maturation of germinal center B cells after influenza virus vaccination in humans.
J.Exp.Med., 221, 2024
8TY7
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BU of 8ty7 by Molmil
Crystal structure of 05.GC.w2.3C10 Fab in complex with H1 HA from A/California/04/2009(H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w2_3C10, heavy chain, ...
著者Lin, T.H, Moore, N, Wilson, I.A.
登録日2023-08-24
公開日2024-06-26
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Maturation of germinal center B cells after influenza virus vaccination in humans.
J.Exp.Med., 221, 2024
8U44
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BU of 8u44 by Molmil
CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06
分子名称: 05.GC.w2.3C10-H1_SI06 Heavy chain, 05.GC.w2.3C10-H1_SI06 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Moore, N, Han, J, Ward, A.B, Wilson, I.A.
登録日2023-09-08
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Persistence of germinal center B cell responses after influenza virus vaccination in humans
To Be Published
8TXP
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BU of 8txp by Molmil
Crystal structure of 05.GC.w13.01 Fab in complex with H1 HA from A/California/04/2009(H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_A, Fab heavy chain, ...
著者Lin, T.H, Moore, N, Wilson, I.A.
登録日2023-08-24
公開日2024-06-26
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Maturation of germinal center B cells after influenza virus vaccination in humans.
J.Exp.Med., 221, 2024
8TXM
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BU of 8txm by Molmil
Crystal structure of 05.GC.w13.02 Fab in complex with H1 HA from A/California/04/2009(H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GC_w13_B, ...
著者Lin, T.H, Moore, N, Wilson, I.A.
登録日2023-08-23
公開日2024-06-26
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Maturation of germinal center B cells after influenza virus vaccination in humans.
J.Exp.Med., 221, 2024
4TOT
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BU of 4tot by Molmil
Crystal structure of rat cyclophilin D in complex with a potent nonimmunosuppressive inhibitor
分子名称: HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ...
著者Knapp, M.S, Elling, R.A.
登録日2014-06-06
公開日2014-11-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
J.Med.Chem., 57, 2014
6JE9
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BU of 6je9 by Molmil
Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers
分子名称: AcrIIC3, CRISPR-associated endonuclease Cas9, sgRNA
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-02-04
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6IFK
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BU of 6ifk by Molmil
Cryo-EM structure of type III-A Csm-CTR1 complex, AMPPNP bound
分子名称: CTR1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者You, L, Ma, J, Wang, J, Zhang, X, Wang, Y.
登録日2018-09-20
公開日2018-12-12
最終更新日2019-01-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IG0
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BU of 6ig0 by Molmil
Type III-A Csm complex, Cryo-EM structure of Csm-CTR1, ATP bound
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CTR1, MAGNESIUM ION, ...
著者You, L, Ma, J, Wang, J, Zhang, X, Wang, Y.
登録日2018-09-21
公開日2018-12-12
最終更新日2019-01-23
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFY
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BU of 6ify by Molmil
Type III-A Csm complex, Cryo-EM structure of Csm-CTR1
分子名称: CTR1, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ...
著者You, L, Ma, J, Wang, J, Zhang, X, Wang, Y.
登録日2018-09-21
公開日2018-12-12
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IMM
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BU of 6imm by Molmil
Cryo-EM structure of an alphavirus, Sindbis virus
分子名称: Assembly protein E3, Octadecane, Spike glycoprotein E1, ...
著者Zhang, X, Ma, J, Chen, L.
登録日2018-10-23
公開日2019-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Implication for alphavirus host-cell entry and assembly indicated by a 3.5 angstrom resolution cryo-EM structure.
Nat Commun, 9, 2018
6IFL
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BU of 6ifl by Molmil
Cryo-EM structure of type III-A Csm-NTR complex
分子名称: NTR, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ...
著者You, L, Ma, J, Wang, J, Zhang, X, Wang, Y.
登録日2018-09-20
公開日2018-12-12
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IK4
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BU of 6ik4 by Molmil
A Novel M23 Metalloprotease Pseudoalterin from Deep-sea
分子名称: Elastinolytic metalloprotease, GLYCEROL, ZINC ION
著者Zhao, H.L, Tang, B.L, Yang, J, Chen, X.L, Zhang, Y.Z.
登録日2018-10-14
公開日2019-10-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria.
Nat Commun, 11, 2020
6ICW
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BU of 6icw by Molmil
Crystal structure of H7 hemagglutinin mutant AH-SGTQ (A138S, V186G, P221T and L226Q) from the influenza virus A/Anhui/1/2013 (H7N9)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
著者Gao, G.F, Xu, Y.
登録日2018-09-07
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Avian-to-Human Receptor-Binding Adaptation of Avian H7N9 Influenza Virus Hemagglutinin.
Cell Rep, 29, 2019
6ID2
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BU of 6id2 by Molmil
Crystal structure of H7 hemagglutinin mutant H7-AVTL (P221T) from the influenza virus A/Anhui/1/2013 (H7N9)
分子名称: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
著者Gao, G.F, Xu, Y, Qi, J.X.
登録日2018-09-08
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Avian-to-Human Receptor-Binding Adaptation of Avian H7N9 Influenza Virus Hemagglutinin.
Cell Rep, 29, 2019
6IF3
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BU of 6if3 by Molmil
Complex structure of Rab35 and its effector ACAP2
分子名称: Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Lin, L, Zhu, J, Zhang, R.
登録日2018-09-18
公開日2019-04-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
6ID5
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BU of 6id5 by Molmil
Crystal structure of H7 hemagglutinin mutant H7-SVPL ( A138S) from the influenza virus A/Anhui/1/2013 (H7N9)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
著者Gao, G.F, Xu, Y, Qi, J.X.
登録日2018-09-08
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Avian-to-Human Receptor-Binding Adaptation of Avian H7N9 Influenza Virus Hemagglutinin.
Cell Rep, 29, 2019

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