3OCX
| Structure of Recombinant Haemophilus influenzae e(P4) Acid Phosphatase mutant D66N complexed with 2'-AMP | 分子名称: | ADENOSINE-2'-MONOPHOSPHATE, Lipoprotein E, MAGNESIUM ION | 著者 | Singh, H, Schuermann, J, Reilly, T, Calcutt, M, Tanner, J. | 登録日 | 2010-08-10 | 公開日 | 2010-10-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Recognition of nucleoside monophosphate substrates by Haemophilus influenzae class C acid phosphatase. J.Mol.Biol., 404, 2010
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8GV1
| Crystal structure of anti-FX IgG fab with FAST-Ig mutations | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Anti-factor X IgG fab heavy chain, ... | 著者 | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | 登録日 | 2022-09-14 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.186 Å) | 主引用文献 | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
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8GUZ
| Crystal structure of anti-FIXa IgG fab with FAST-Ig mutations | 分子名称: | 1,2-ETHANEDIOL, Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain | 著者 | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | 登録日 | 2022-09-14 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
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8GV2
| Crystal structure of anti-FX IgG fab without FAST-Ig mutations | 分子名称: | 1,2-ETHANEDIOL, Anti-factor X IgG fab heavy chain, Anti-factor X IgG fab light chain | 著者 | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | 登録日 | 2022-09-14 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.274 Å) | 主引用文献 | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
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8GV0
| Crystal structure of anti-FIXa IgG fab without FAST-Ig mutations | 分子名称: | Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain | 著者 | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | 登録日 | 2022-09-14 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.192 Å) | 主引用文献 | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A. Mabs, 15, 2023
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8GZC
| Crystal structure of EP300 HAT domain in complex with compound 10 | 分子名称: | (2~{R},4~{R})-4-fluoranyl-1-[1-(4-methoxyphenyl)cyclohexyl]carbonyl-~{N}-(1~{H}-pyrazolo[4,3-b]pyridin-5-yl)pyrrolidine-2-carboxamide, Histone acetyltransferase p300, ZINC ION | 著者 | Takahashi, M, Hanzawa, H. | 登録日 | 2022-09-26 | 公開日 | 2023-01-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor. J.Med.Chem., 66, 2023
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2DKV
| Crystal structure of class I chitinase from Oryza sativa L. japonica | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, chitinase | 著者 | Kezuka, Y, Nishizawa, Y, Watanabe, T, Nonaka, T. | 登録日 | 2006-04-14 | 公開日 | 2007-05-01 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of full-length class I chitinase from rice revealed by X-ray crystallography and small-angle X-ray scattering. Proteins, 78, 2010
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8S5I
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8S5L
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8S5J
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8S5K
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8S5H
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8S5M
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5VTA
| Co-Crystal Structure of DPPIV with a Chemibody Inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]piperazin-1-yl}-N-(22-oxo-3,6,9,12,15,18-hexaoxa-21-azatricosan-1-yl)acetamide, ... | 著者 | Wang, Z, Johnstone, S, Cheng, A. | 登録日 | 2017-05-16 | 公開日 | 2018-05-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-guided Discovery of Dual-recognition Chemibodies. Sci Rep, 8, 2018
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3OCV
| Structure of Recombinant Haemophilus Influenzae e(P4) Acid Phosphatase mutant D66N complexed with 5'-AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Lipoprotein E, MAGNESIUM ION | 著者 | Singh, H, Schuermann, J, Reilly, T, Calcutt, M, Tanner, J. | 登録日 | 2010-08-10 | 公開日 | 2010-10-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.551 Å) | 主引用文献 | Recognition of nucleoside monophosphate substrates by Haemophilus influenzae class C acid phosphatase. J.Mol.Biol., 404, 2010
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3OCW
| Structure of Recombinant Haemophilus influenzae e(P4) Acid Phosphatase mutant D66N complexed with 3'-AMP | 分子名称: | Lipoprotein E, MAGNESIUM ION, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate | 著者 | Singh, H, Schuermann, J, Reilly, T, Calcutt, M, Tanner, J. | 登録日 | 2010-08-10 | 公開日 | 2010-10-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Recognition of nucleoside monophosphate substrates by Haemophilus influenzae class C acid phosphatase. J.Mol.Biol., 404, 2010
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3OCY
| Structure of Recombinant Haemophilus Influenzae e(P4) Acid Phosphatase Complexed with inorganic phosphate | 分子名称: | Lipoprotein E, MAGNESIUM ION, PHOSPHATE ION | 著者 | Singh, H, Schuermann, J, Reilly, T, Calcutt, M, Tanner, J. | 登録日 | 2010-08-10 | 公開日 | 2010-10-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Recognition of nucleoside monophosphate substrates by Haemophilus influenzae class C acid phosphatase. J.Mol.Biol., 404, 2010
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3OCU
| Structure of Recombinant Haemophilus Influenzae e(P4) Acid Phosphatase mutant D66N complexed with NMN | 分子名称: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Lipoprotein E, MAGNESIUM ION | 著者 | Singh, H, Schuermann, J, Reilly, T, Calcutt, M, Tanner, J. | 登録日 | 2010-08-10 | 公開日 | 2010-10-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Recognition of nucleoside monophosphate substrates by Haemophilus influenzae class C acid phosphatase. J.Mol.Biol., 404, 2010
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6QAM
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6EOY
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4APE
| THE ACTIVE SITE OF ASPARTIC PROTEINASES | 分子名称: | ENDOTHIAPEPSIN | 著者 | Pearl, L.H, Sewell, B.T, Jenkins, J.A, Cooper, J.B, Blundell, T.L. | 登録日 | 1986-06-09 | 公開日 | 1986-07-14 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Active Site of Aspartic Proteinases FEBS Lett., 174, 1984
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6QWR
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7RWF
| Crystal structure of CDK2 in complex with TW8672 | 分子名称: | 1,2-ETHANEDIOL, 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-nitrobenzoic acid, Cyclin-dependent kinase 2 | 著者 | Sun, L, Schonbrunn, E. | 登録日 | 2021-08-19 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nat Commun, 14, 2023
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7S84
| Crystal structure of CDK2 liganded with compound TW8972 | 分子名称: | 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-(trifluoromethyl)benzoic acid, Cyclin-dependent kinase 2 | 著者 | Sun, L, Schonbrunn, E. | 登録日 | 2021-09-17 | 公開日 | 2022-09-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nat Commun, 14, 2023
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6R71
| Crystal structure of human carbonic anhydrase isozyme XII with 2-(benzenesulfonyl)-4-chloro-N-(2-hydroxyethyl)-5-sulfamoyl-benzamide | 分子名称: | 1,2-ETHANEDIOL, 4-chloranyl-~{N}-(2-hydroxyethyl)-2-(phenylsulfonyl)-5-sulfamoyl-benzamide, Carbonic anhydrase 12, ... | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | 登録日 | 2019-03-28 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms. Eur.J.Med.Chem., 185, 2020
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