7ACU
Crystal structure of human transthyretin in complex with Benzbromarone
Summary for 7ACU
Entry DOI | 10.2210/pdb7acu/pdb |
Descriptor | Transthyretin, [3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-1-benzofuran-3-yl)methanone (3 entities in total) |
Functional Keywords | transthyretin, ttr, benzbromarone, complex, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 26060.37 |
Authors | Leite, J.P.,Gales, L. (deposition date: 2020-09-11, release date: 2020-10-28, Last modification date: 2024-01-31) |
Primary citation | Cotrina, E.Y.,Oliveira, A.,Leite, J.P.,Llop, J.,Gales, L.,Quintana, J.,Cardoso, I.,Arsequell, G. Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer. Int J Mol Sci, 21:-, 2020 Cited by PubMed: 32998442DOI: 10.3390/ijms21197166 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.541 Å) |
Structure validation
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