6IZN

Crystal structure of the PPARgamma-LBD complexed with compound 3g

Summary for 6IZN

• Entry DOI: 10.2210/pdb6izn/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, 3-[[6-(2,6-dimethylpyridin-3-yl)oxy-7-fluoranyl-1-methyl-benzimidazol-2-yl]methoxy]benzoic acid, ... (4 entities in total)
• Functional Keywords: transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 34901.38

Authors

Matsui, Y.,Hanzawa, H. (deposition date: 2018-12-20, release date: 2019-03-27, Last modification date: 2023-11-22)

• Primary citation: Shinozuka, T.,Tsukada, T.,Fujii, K.,Tokumaru, E.,Matsui, Y.,Wakimoto, S.,Ogata, T.,Araki, K.,Sawamura, R.,Watanabe, N.,Mori, M.,Tanaka, J.; Structure-Activity Relationship Studies of 3- or 4-Pyridine Derivatives of DS-6930.; Acs Med.Chem.Lett., 10:358-362, 2019; PubMed: 30891140; DOI: 10.1021/acsmedchemlett.8b00645

Experimental method

X-RAY DIFFRACTION (1.75 Å)