4ORB
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![BU of 4orb by Molmil](/molmil-images/mine/4orb) | Crystal structure of mouse calcineurin | 分子名称: | CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... | 著者 | Ma, L, Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. | 登録日 | 2014-02-11 | 公開日 | 2015-05-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.108 Å) | 主引用文献 | Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
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4ORC
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![BU of 4orc by Molmil](/molmil-images/mine/4orc) | Crystal structure of mammalian calcineurin | 分子名称: | CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... | 著者 | Ma, L, Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. | 登録日 | 2014-02-11 | 公開日 | 2015-05-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
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1R5H
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![BU of 1r5h by Molmil](/molmil-images/mine/1r5h) | Crystal Structure of MetAP2 complexed with A320282 | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-(2S,3R)-3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTANO-N-(4-METHYLPHENYL)HYDRAZIDE | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | 登録日 | 2003-10-10 | 公開日 | 2004-10-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2. Bioorg.Med.Chem.Lett., 14, 2004
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1R58
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![BU of 1r58 by Molmil](/molmil-images/mine/1r58) | Crystal Structure of MetAP2 complexed with A357300 | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Ericken, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | 登録日 | 2003-10-09 | 公開日 | 2004-10-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2. Bioorg.Med.Chem.Lett., 14, 2004
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7EOD
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![BU of 7eod by Molmil](/molmil-images/mine/7eod) | MITF HLHLZ Delta AKE | 分子名称: | GLYCEROL, Isoform M1 of Microphthalmia-associated transcription factor | 著者 | Li, P, Liu, Z, Fang, P, Wang, J. | 登録日 | 2021-04-22 | 公開日 | 2022-04-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res., 33, 2023
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4OR9
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![BU of 4or9 by Molmil](/molmil-images/mine/4or9) | Crystal structure of human calcineurin | 分子名称: | CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... | 著者 | Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. | 登録日 | 2014-02-11 | 公開日 | 2015-05-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
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4JGY
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![BU of 4jgy by Molmil](/molmil-images/mine/4jgy) | Crystal structure of human coxsackievirus A16 uncoating intermediate (space group P4232) | 分子名称: | Polyprotein, capsid protein VP1, capsid protein VP2, ... | 著者 | Ren, J, Wang, X, Hu, Z, Gao, Q, Sun, Y, Li, X, Porta, C, Walter, T.S, Gilbert, R.J, Zhao, Y, Axford, D, Williams, M, Mcauley, K, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | 登録日 | 2013-03-04 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Picornavirus uncoating intermediate captured in atomic detail. Nat Commun, 4, 2013
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5ZCS
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![BU of 5zcs by Molmil](/molmil-images/mine/5zcs) | 4.9 Angstrom Cryo-EM structure of human mTOR complex 2 | 分子名称: | Rapamycin-insensitive companion of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex 2 subunit MAPKAP1, ... | 著者 | Chen, X, Liu, M, Tian, Y, Wang, H, Wang, J, Xu, Y. | 登録日 | 2018-02-20 | 公開日 | 2018-03-21 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Cryo-EM structure of human mTOR complex 2. Cell Res., 28, 2018
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8H99
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![BU of 8h99 by Molmil](/molmil-images/mine/8h99) | Crystal structure of E. coli ThrS catalytic domain mutant | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, IMIDAZOLE, MAGNESIUM ION, ... | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | 登録日 | 2022-10-25 | 公開日 | 2023-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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8H9C
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![BU of 8h9c by Molmil](/molmil-images/mine/8h9c) | Crystal structure of chemically modified E. coli ThrS catalytic domain 4 | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | 登録日 | 2022-10-25 | 公開日 | 2023-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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8H98
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![BU of 8h98 by Molmil](/molmil-images/mine/8h98) | Crystal structure of chemically modified E. coli ThrS catalytic domain 1 | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | 登録日 | 2022-10-25 | 公開日 | 2023-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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8H9B
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![BU of 8h9b by Molmil](/molmil-images/mine/8h9b) | Crystal structure of chemically modified E. coli ThrS catalytic domain 3 | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | 登録日 | 2022-10-25 | 公開日 | 2023-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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8H9A
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![BU of 8h9a by Molmil](/molmil-images/mine/8h9a) | Crystal structure of chemically modified E. coli ThrS catalytic domain 2 | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | 登録日 | 2022-10-25 | 公開日 | 2023-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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8KA0
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![BU of 8ka0 by Molmil](/molmil-images/mine/8ka0) | Crystal structure of Vibrio vulnificus RID-dependent transforming NADase domain (RDTND)/calmodulin-binding domain of Rho inactivation domain (RID-CBD) complexed with Ca2+-bound calmodulin and a nicotinamide adenine dinucleotide (NAD+) | 分子名称: | CALCIUM ION, Calmodulin-2, GLYCEROL, ... | 著者 | Lee, Y, Choi, S, Hwang, J, Kim, M.H. | 登録日 | 2023-08-02 | 公開日 | 2024-07-10 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Dissemination of pathogenic bacteria is reinforced by a MARTX toxin effector duet. Nat Commun, 15, 2024
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8KA2
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![BU of 8ka2 by Molmil](/molmil-images/mine/8ka2) | |
8K9Z
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![BU of 8k9z by Molmil](/molmil-images/mine/8k9z) | Crystal structure of Vibrio vulnificus RID-dependent transforming NADase domain (RDTND)/calmodulin-binding domain of Rho inactivation domain (RID-CBD) complexed with Ca2+-bound calmodulin | 分子名称: | CALCIUM ION, Calmodulin-2, RDTND-RID CBD | 著者 | Lee, Y, Choi, S, Hwang, J, Kim, M.H. | 登録日 | 2023-08-02 | 公開日 | 2024-07-10 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Dissemination of pathogenic bacteria is reinforced by a MARTX toxin effector duet. Nat Commun, 15, 2024
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8KA1
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![BU of 8ka1 by Molmil](/molmil-images/mine/8ka1) | Crystal structure of Vibrio vulnificus RID-dependent transforming NADase domain (RDTND)/calmodulin-binding domain of Rho inactivation domain (RID-CBD) complexed with Ca2+-free calmodulin | 分子名称: | Calmodulin-2, MAGNESIUM ION, RDTND-RID CBD | 著者 | Lee, Y, Choi, S, Hwang, J, Kim, M.H. | 登録日 | 2023-08-02 | 公開日 | 2024-07-10 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Dissemination of pathogenic bacteria is reinforced by a MARTX toxin effector duet. Nat Commun, 15, 2024
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7C4U
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![BU of 7c4u by Molmil](/molmil-images/mine/7c4u) | MicroED structure of orthorhombic Vancomycin at 1.2 A resolution | 分子名称: | CHLORIDE ION, Vancomycin, vancosamine-(1-2)-beta-D-glucopyranose | 著者 | Fan, Q, Zhou, H, Li, X, Wang, J. | 登録日 | 2020-05-18 | 公開日 | 2020-08-12 | 最終更新日 | 2021-03-17 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.2 Å) | 主引用文献 | Precise Control Over Kinetics of Molecular Assembly: Production of Particles with Tunable Sizes and Crystalline Forms. Angew.Chem.Int.Ed.Engl., 59, 2020
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5ZM7
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![BU of 5zm7 by Molmil](/molmil-images/mine/5zm7) | Crystal structure of ORP1-ORD in complex with cholesterol at 3.4 A resolution | 分子名称: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | 著者 | Dong, J, Wang, J, Wu, J.W. | 登録日 | 2018-04-01 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.401 Å) | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2. Nat Commun, 10, 2019
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7C4V
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![BU of 7c4v by Molmil](/molmil-images/mine/7c4v) | MicroED structure of anorthic Vancomycin at 1.05 A resolution | 分子名称: | CHLORIDE ION, Vancomycin, vancosamine-(1-2)-beta-D-glucopyranose | 著者 | Fan, Q, Zhou, H, Li, X, Wang, J. | 登録日 | 2020-05-18 | 公開日 | 2020-08-12 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.05 Å) | 主引用文献 | Precise Control Over Kinetics of Molecular Assembly: Production of Particles with Tunable Sizes and Crystalline Forms. Angew.Chem.Int.Ed.Engl., 59, 2020
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1R5G
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![BU of 1r5g by Molmil](/molmil-images/mine/1r5g) | Crystal Structure of MetAP2 complexed with A311263 | 分子名称: | (2S,3R)-3-AMINO-2-HYDROXY-5-(ETHYLSULFANYL)PENTANOYL-((S)-(-)-(1-NAPHTHYL)ETHYL)AMIDE, MANGANESE (II) ION, Methionine aminopeptidase 2 | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | 登録日 | 2003-10-10 | 公開日 | 2004-10-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2. Bioorg.Med.Chem.Lett., 14, 2004
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6IFZ
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![BU of 6ifz by Molmil](/molmil-images/mine/6ifz) | Type III-A Csm complex, Cryo-EM structure of Csm-CTR2-ssDNA complex | 分子名称: | CTR2, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-21 | 公開日 | 2018-12-12 | 最終更新日 | 2019-01-23 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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4JGZ
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![BU of 4jgz by Molmil](/molmil-images/mine/4jgz) | Crystal structure of human coxsackievirus A16 uncoating intermediate (space group I222) | 分子名称: | Polyprotein, capsid protein VP1, capsid protein VP2, ... | 著者 | Ren, J, Wang, X, Hu, Z, Gao, Q, Sun, Y, Li, X, Porta, C, Walter, T.S, Gilbert, R.J, Zhao, Y, Axford, D, Williams, M, McAuley, K, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | 登録日 | 2013-03-04 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Picornavirus uncoating intermediate captured in atomic detail. Nat Commun, 4, 2013
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5ZM5
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![BU of 5zm5 by Molmil](/molmil-images/mine/5zm5) | Crystal structure of human ORP1-ORD in complex with cholesterol at 2.6 A resolution | 分子名称: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | 著者 | Dong, J, Wang, J, Wu, J.W. | 登録日 | 2018-04-01 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2. Nat Commun, 10, 2019
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6CYW
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![BU of 6cyw by Molmil](/molmil-images/mine/6cyw) | Structure of sphingomyelin in complex with mouse CD1d | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | 著者 | Zajonc, D.M, Wang, J. | 登録日 | 2018-04-06 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. Nat.Immunol., 20, 2019
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