7EOD

MITF HLHLZ Delta AKE

Summary for 7EOD

Entry DOI	10.2210/pdb7eod/pdb
Descriptor	Isoform M1 of Microphthalmia-associated transcription factor, GLYCEROL (3 entities in total)
Functional Keywords	transcription factor, transcription
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	35961.43
Authors	Li, P.,Liu, Z.,Fang, P.,Wang, J. (deposition date: 2021-04-22, release date: 2022-04-27, Last modification date: 2023-11-29)
Primary citation	Liu, Z.,Chen, K.,Dai, J.,Xu, P.,Sun, W.,Liu, W.,Zhao, Z.,Bennett, S.P.,Li, P.,Ma, T.,Lin, Y.,Kawakami, A.,Yu, J.,Wang, F.,Wang, C.,Li, M.,Chase, P.,Hodder, P.,Spicer, T.P.,Scampavia, L.,Cao, C.,Pan, L.,Dong, J.,Chen, Y.,Yu, B.,Guo, M.,Fang, P.,Fisher, D.E.,Wang, J. A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res., 33:55-70, 2023 Cited by PubMed: 36588115 DOI: 10.1038/s41422-022-00744-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation