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5OEQ
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BU of 5oeq by Molmil
Mycobacterium tuberculosis DprE1 in complex with inhibitor TCA020
分子名称: Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, ...
著者Futterer, K, Batt, S.M, Besra, G.S.
登録日2017-07-09
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes.
Angew. Chem. Int. Ed. Engl., 56, 2017
5WPW
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BU of 5wpw by Molmil
Crystal structure of coconut allergen cocosin
分子名称: 11S globulin isoform 1
著者Jin, T, Zhang, Y.
登録日2016-11-21
公開日2017-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.847 Å)
主引用文献Crystal Structure of Cocosin, A Potential Food Allergen from Coconut (Cocos nucifera)
J. Agric. Food Chem., 65, 2017
5J3G
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BU of 5j3g by Molmil
Solution NMR structure of PT-free dsDNA from Streptomyces lividans
分子名称: DNA (5'-D(*CP*GP*GP*CP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*GP*CP*GP*GP*CP*CP*G)-3')
著者Lan, W, Cao, C.
登録日2016-03-30
公開日2016-06-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural investigation into physiological DNA phosphorothioate modification
Sci Rep, 6, 2016
7VHQ
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BU of 7vhq by Molmil
Structural insights into the membrane microdomain organization by SPFH family proteins
分子名称: ATP-dependent zinc metalloprotease FtsH, Modulator of FtsH protease HflC, Protein HflK
著者Ma, C.Y, Wang, C.K, Luo, D.Y, Yan, L, Yang, W.X, Li, N.N, Gao, N.
登録日2021-09-22
公開日2022-01-19
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structural insights into the membrane microdomain organization by SPFH family proteins.
Cell Res., 32, 2022
7VHP
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BU of 7vhp by Molmil
Structural insights into the membrane microdomain organization by SPFH family proteins
分子名称: ATP-dependent zinc metalloprotease FtsH, Modulator of FtsH protease HflC, Protein HflK
著者Ma, C.Y, Wang, C.K, Luo, D.Y, Yan, L, Yang, W.X, Li, N.N, Gao, N.
登録日2021-09-22
公開日2022-03-23
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structural insights into the membrane microdomain organization by SPFH family proteins.
Cell Res., 32, 2022
4HKF
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BU of 4hkf by Molmil
Crystal structure of Danio rerio MEC-17 catalytic domain in complex with acetyl-CoA
分子名称: ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, SULFATE ION
著者Li, W, Zhong, C, Sun, B, Xu, S, Zhang, T, Ding, J.
登録日2012-10-15
公開日2012-12-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis of the acetyltransferase activity of MEC-17 towards alpha- tubulin
Cell Res., 22, 2012
6MNL
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BU of 6mnl by Molmil
NMR solution structures of second bromodomain of BRD4 with FOXO3a peptide
分子名称: Bromodomain-containing protein 4, FOXO3a peptide
著者Zeng, L, Zhou, M.-M.
登録日2018-10-02
公開日2018-10-31
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Nat Commun, 9, 2018
8JEC
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BU of 8jec by Molmil
plant potassium channel SKOR mutant - L271P/D312N
分子名称: Potassium channel SKOR
著者Liu, S, Li, S, Tian, C.
登録日2023-05-15
公開日2023-08-30
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure reveals a symmetry reduction of the plant outward-rectifier potassium channel SKOR.
Cell Discov, 9, 2023
8JEU
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BU of 8jeu by Molmil
Conformation 2 of the plant potassium channel SKOR
分子名称: Potassium channel SKOR
著者Liu, S, Li, S, Sun, D, Tian, C.
登録日2023-05-16
公開日2023-08-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure reveals a symmetry reduction of the plant outward-rectifier potassium channel SKOR.
Cell Discov, 9, 2023
8JET
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BU of 8jet by Molmil
Conformation 1 of the plant potassium channel SKOR
分子名称: Potassium channel SKOR
著者Liu, S, Li, S, Sun, D, Tian, C.
登録日2023-05-16
公開日2023-08-30
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure reveals a symmetry reduction of the plant outward-rectifier potassium channel SKOR.
Cell Discov, 9, 2023
5Z9R
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BU of 5z9r by Molmil
NMNAT as a specific chaperone antagonizing pathological condensation of phosphorylated tau
分子名称: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
著者Dou, S, Ma, X, Li, D, Liu, C.
登録日2018-02-05
公開日2019-02-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Nicotinamide mononucleotide adenylyltransferase uses its NAD+substrate-binding site to chaperone phosphorylated Tau.
Elife, 9, 2020
8JGF
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BU of 8jgf by Molmil
CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22
分子名称: BAM8-22, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Sun, J.P, Xu, H.E, Yang, F, Liu, Z.M, Guo, L.L, Zhang, Y.M, Fang, G.X, Tie, L, Zhuang, Y.M, Xue, C.Y.
登録日2023-05-20
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.
Nat Commun, 14, 2023
8JGG
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BU of 8jgg by Molmil
CryoEM structure of Gi-coupled MRGPRX1 with peptide agonist BAM8-22
分子名称: BAM8-22, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Sun, J.P, Xu, H.E, Ynag, F, Liu, Z.M, Guo, L.L, Zhang, Y.M, Fang, G.X, Tie, L, Zhuang, Y.M, Xue, C.Y.
登録日2023-05-20
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.
Nat Commun, 14, 2023
8JGB
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BU of 8jgb by Molmil
CryoEM structure of Gi-coupled MRGPRX1 with peptide agonist CNF-Tx2
分子名称: Conorfamide-Tx2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Sun, J.P, Xu, H.E, Yang, F, Liu, Z.M, Guo, L.L, Zhang, Y.M, Fang, G.X, Tie, L, Zhuang, Y.M, Xue, C.Y.
登録日2023-05-20
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.
Nat Commun, 14, 2023
5E2O
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BU of 5e2o by Molmil
FACTOR XIA IN COMPLEX WITH THE INHIBITOR 4-[(N-{(2E)-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enoyl}-L-phenylalanyl)amino]benzoic acid
分子名称: 1,2-ETHANEDIOL, 4-[(N-{(2E)-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enoyl}-L-phenylalanyl)amino]benzoic acid, Coagulation factor XIa light chain, ...
著者Wei, A.
登録日2015-10-01
公開日2015-12-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Novel phenylalanine derived diamides as Factor XIa inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5E2P
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BU of 5e2p by Molmil
FACTOR XIA IN COMPLEX WITH THE INHIBITOR N-[(1S)-1-benzyl-2-[2-[5-chloro-2-(tetrazol-1-yl)phenyl]ethylamino]-2-oxo-ethyl]-4-hydroxy-2-oxo-1H-quinoline-6-carboxamide
分子名称: 1,2-ETHANEDIOL, Coagulation factor XIa light chain, N-[(1S)-1-benzyl-2-[2-[5-chloro-2-(tetrazol-1-yl)phenyl]ethylamino]-2-oxo-ethyl]-4-hydroxy-2-oxo-1H-quinoline-6-carboxamide, ...
著者Wei, A.
登録日2015-10-01
公開日2015-12-09
最終更新日2016-01-20
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Novel phenylalanine derived diamides as Factor XIa inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5H7P
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BU of 5h7p by Molmil
NMR structure of the Vta1NTD-Did2(176-204) complex
分子名称: Vacuolar protein sorting-associated protein VTA1, Vacuolar protein-sorting-associated protein 46
著者Shen, J, Yang, Z, Wild, C.J.
登録日2016-11-20
公開日2016-12-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR studies on the interactions between yeast Vta1 and Did2 during the multivesicular bodies sorting pathway
Sci Rep, 6, 2016
6B0F
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BU of 6b0f by Molmil
ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH LSZ102
分子名称: Estrogen receptor, GLYCEROL, LSZ102
著者Kirby, C.A, Baird, J.
登録日2017-09-14
公開日2018-04-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
J. Med. Chem., 61, 2018
5BOF
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BU of 5bof by Molmil
Crystal Structure of Staphylococcus aureus Enolase
分子名称: Enolase, MAGNESIUM ION, SULFATE ION
著者Wu, Y.F, Wang, C.L, Wu, M.H, Han, L, Zhang, X, Zang, J.Y.
登録日2015-05-27
公開日2015-12-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Octameric structure of Staphylococcus aureus enolase in complex with phosphoenolpyruvate.
Acta Crystallogr.,Sect.D, 71, 2015
6W19
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BU of 6w19 by Molmil
Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus
分子名称: Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ...
著者Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H.
登録日2020-03-03
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus.
Nat Microbiol, 5, 2020
6W2E
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BU of 6w2e by Molmil
Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus
分子名称: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ...
著者Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H.
登録日2020-03-05
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus.
Nat Microbiol, 5, 2020
8TJF
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BU of 8tjf by Molmil
monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface
分子名称: Fab Lambda light chain, IgG1 Fab heavy chain
著者Oganesyan, V.Y, van Dyk, N, Mazor, Y, Chiang, C.
登録日2023-07-21
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface.
Mabs, 15, 2023
7YUU
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BU of 7yuu by Molmil
MtaLon-ADP for the spiral oligomers of trimer
分子名称: Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-17
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
7YUV
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BU of 7yuv by Molmil
MtaLon-ADP for the spiral oligomers of tetramer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-17
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
7YUW
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BU of 7yuw by Molmil
MtaLon-ADP for the spiral oligomers of pentamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-18
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023

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