5Z9R
NMNAT as a specific chaperone antagonizing pathological condensation of phosphorylated tau
Summary for 5Z9R
Entry DOI | 10.2210/pdb5z9r/pdb |
Descriptor | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (2 entities in total) |
Functional Keywords | antagonizing pathological condensation of phosphorylated tau, chaperone, transferase |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 2 |
Total formula weight | 63145.95 |
Authors | |
Primary citation | Ma, X.,Zhu, Y.,Lu, J.,Xie, J.,Li, C.,Shin, W.S.,Qiang, J.,Liu, J.,Dou, S.,Xiao, Y.,Wang, C.,Jia, C.,Long, H.,Yang, J.,Fang, Y.,Jiang, L.,Zhang, Y.,Zhang, S.,Zhai, R.G.,Liu, C.,Li, D. Nicotinamide mononucleotide adenylyltransferase uses its NAD+substrate-binding site to chaperone phosphorylated Tau. Elife, 9:-, 2020 Cited by PubMed: 32250733DOI: 10.7554/eLife.51859 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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