5Z9R

NMNAT as a specific chaperone antagonizing pathological condensation of phosphorylated tau

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3	polymer	281	31573.0	2	UniProt (Q99JR6) Pfam (PF01467)	Mus musculus (Mouse)	NMN/NaMN adenylyltransferase 3,Nicotinamide-nucleotide adenylyltransferase 3,NMN adenylyltransferase 3,Nicotinate-nucleotide adenylyltransferase 3,NaMN adenylyltransferase 3
2	C, D (A, B)	water	water		18.0	215	Chemie (HOH)

Sequence modifications

A, B: 1 - 245 (UniProt: Q99JR6)

PDB	External Database	Details
Met -35	-	expression tag
Gly -34	-	expression tag
Ser -33	-	expression tag
Ser -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
Ser -25	-	expression tag
Ser -24	-	expression tag
Gly -23	-	expression tag
Leu -22	-	expression tag
Val -21	-	expression tag
Pro -20	-	expression tag
Arg -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
Met -15	-	expression tag
Ala -14	-	expression tag
Ser -13	-	expression tag
Met -12	-	expression tag
Thr -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Gln -8	-	expression tag
Gln -7	-	expression tag
Met -6	-	expression tag
Gly -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63145.9
All*	Total formula weight	63145.9

*Water molecules are not included.