7XWZ
 
 | | Crystal structure of SARS-CoV-2 N-NTD and dsRNA complex | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Nucleoprotein, ... | | 著者 | Luan, X.D, Li, X.M, Li, Y.F. | | 登録日 | 2022-05-27 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein.
Sci Bull (Beijing), 67, 2022
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8AYT
 | | Crystal structure of SUDV VP40 W95A mutant | | 分子名称: | Matrix protein VP40 | | 著者 | Werner, A.-D, Steinchen, W, Werel, L, Kowalski, K, Essen, L.-O, Becker, S. | | 登録日 | 2022-09-03 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of SUDV VP40 W95A mutant
To Be Published
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8AYU
 | | Crystal structure of SUDV VP40 L117A mutant | | 分子名称: | Matrix protein VP40 | | 著者 | Werner, A.-D, Steinchen, W, Werel, L, Kowalski, K, Essen, L.-O, Becker, S. | | 登録日 | 2022-09-03 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of SUDV VP40 L117A mutant
To Be Published
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6J24
 | | Crystal structure of a SAM-dependent methyltransferase LepI in complex with its substrate | | 分子名称: | (3~{S},4'~{R},4'~{a}~{S},6'~{R},8'~{a}~{S})-4',6'-dimethyl-5-phenyl-spiro[1~{H}-pyridine-3,5'-2,3,4,4~{a},6,8~{a}-hexahydro-1~{H}-naphthalene]-2,4-dione, O-methyltransferase, S-ADENOSYLMETHIONINE | | 著者 | Qiu, S, Wei, C. | | 登録日 | 2018-12-30 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.244 Å) | | 主引用文献 | Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme.
Signal Transduct Target Ther, 4, 2019
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6J9F
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6J9E
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6J1O
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6J46
 | | LepI-SAH complex structure | | 分子名称: | O-methyltransferase lepI, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Qiu, S, Wei, C. | | 登録日 | 2019-01-08 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.621 Å) | | 主引用文献 | Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme.
Signal Transduct Target Ther, 4, 2019
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5I4R
 | | Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (trypsin-modified) | | 分子名称: | Contact-dependent inhibitor A, Contact-dependent inhibitor I, Elongation factor Tu, ... | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2016-02-12 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
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8Q0N
 | | HACE1 in complex with RAC1 Q61L | | 分子名称: | E3 ubiquitin-protein ligase HACE1, GUANOSINE-5'-TRIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ... | | 著者 | Wolter, M, Duering, J, Dienemann, C, Lorenz, S. | | 登録日 | 2023-07-28 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1.
Nat.Struct.Mol.Biol., 31, 2024
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8PWL
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5HKQ
 | | Crystal structure of CDI complex from Escherichia coli STEC_O31 | | 分子名称: | CdiI immunity protein, Contact-dependent inhibitor A | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2016-01-14 | | 公開日 | 2017-01-18 | | 最終更新日 | 2020-03-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Functional plasticity of antibacterial EndoU toxins.
Mol.Microbiol., 109, 2018
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6CP9
 | | Contact-dependent growth inhibition toxin - immunity protein complex from Klebsiella pneumoniae 342 | | 分子名称: | CdiA, CdiI | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2018-03-13 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins.
Structure, 27, 2019
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6CP8
 | | Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CdiA, CdiI, ... | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2018-03-13 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins.
Structure, 27, 2019
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3LFM
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7XR1
 | | Crystal structure of T2R-TTL-3a complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-6-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine, CALCIUM ION, ... | | 著者 | Lun, T, Wu, C.Y. | | 登録日 | 2022-05-09 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Crystal structure of T2R-TTL-3a complex
To Be Published
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7XR0
 | | Crystal structure of T2R-TTL-27a complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-5-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine, CALCIUM ION, ... | | 著者 | Lun, T, Wu, C.Y. | | 登録日 | 2022-05-09 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of T2R-TTL-27a complex
To Be Published
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7AXS
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7AXU
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7AXQ
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7AXX
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7AXP
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7A6S
 | | Crystal Structure of Asn173Ser variant of Human Deoxyhypusine Synthase | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Deoxyhypusine synthase, ... | | 著者 | Wator, E, Wilk, P, Grudnik, P. | | 登録日 | 2020-08-26 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders.
Nat Commun, 14, 2023
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7A6T
 | | Crystal Structure of Asn173Ser variant of Human Deoxyhypusine Synthase in complex with NAD and spermidine | | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Deoxyhypusine synthase, ... | | 著者 | Wator, E, Wilk, P, Grudnik, P. | | 登録日 | 2020-08-26 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders.
Nat Commun, 14, 2023
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3RN4
 | | Crystal structure of iron-substituted Sod2 from Saccharomyces cerevisiae | | 分子名称: | FE (III) ION, Superoxide dismutase [Mn], mitochondrial | | 著者 | Kang, Y, He, Y.-X, Cheng, W, Zhou, C.-Z, Li, W.-F. | | 登録日 | 2011-04-21 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structures of native and Fe-substituted SOD2 from Saccharomyces cerevisiae
Acta Crystallogr.,Sect.F, 67, 2011
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