7XWZ

Crystal structure of SARS-CoV-2 N-NTD and dsRNA complex

Summary for 7XWZ

• Entry DOI: 10.2210/pdb7xwz/pdb
• Descriptor: Nucleoprotein, RNA (5'-R(*CP*AP*CP*UP*GP*AP*C)-3'), RNA (5'-R(P*GP*UP*CP*AP*GP*UP*G)-3'), ... (6 entities in total)
• Functional Keywords: structural protein, drug target, viral protein, viral protein-dna complex, viral protein/dna
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 6
• Total formula weight: 36686.61

Authors

Luan, X.D.,Li, X.M.,Li, Y.F. (deposition date: 2022-05-27, release date: 2023-02-08, Last modification date: 2023-11-29)

• Primary citation: Luan, X.,Li, X.,Li, Y.,Su, G.,Yin, W.,Jiang, Y.,Xu, N.,Wang, F.,Cheng, W.,Jin, Y.,Zhang, L.,Xu, H.E.,Xue, Y.,Zhang, S.; Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein.; Sci Bull (Beijing), 67:2327-2335, 2022; PubMed: 36317101; DOI: 10.1016/j.scib.2022.10.021

Experimental method

X-RAY DIFFRACTION (2.25 Å)